Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study
Tomohito Tanaka,1 Shunsuke Miyamoto,1 Shinichi Terada,1 Yuhei Kogata,1 Hiroshi Sasaki,1 Satoshi Tsunetoh,1 Takashi Yamada,2 Masahide Ohmichi11Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Japan; 2Department of Pathology, Osaka Medical College, Takatsuki, JapanPurpose: Al...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-07-01
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| Series: | Cancer Management and Research |
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| Online Access: | https://www.dovepress.com/intraperitoneal-cytology-after-laparoscopic-radical-hysterectomy-with--peer-reviewed-article-CMAR |
| _version_ | 1818287398796132352 |
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| author | Tanaka T Miyamoto S Terada S Kogata Y Sasaki H Tsunetoh S Yamada T Ohmichi M |
| author_facet | Tanaka T Miyamoto S Terada S Kogata Y Sasaki H Tsunetoh S Yamada T Ohmichi M |
| author_sort | Tanaka T |
| collection | DOAJ |
| description | Tomohito Tanaka,1 Shunsuke Miyamoto,1 Shinichi Terada,1 Yuhei Kogata,1 Hiroshi Sasaki,1 Satoshi Tsunetoh,1 Takashi Yamada,2 Masahide Ohmichi11Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Japan; 2Department of Pathology, Osaka Medical College, Takatsuki, JapanPurpose: Although laparoscopic radical hysterectomy (LRH) has been performed for patients with cervical cancer because of its minimal invasiveness, a recent large prospective study showed that LRH was associated with a lower rate of disease-free survival and overall survival. However, the reason for these results is not apparent. The aim of this study was to evaluate the tumor spillage during LRH with vaginal closure without the use of a manipulator.Patients and methods: Twenty-four patients with cervical cancer underwent total LRH with vaginal closure. To evaluate the leakage of cancer cells during surgery, peritoneal cytology was performed before and after hysterectomy.Results: Among 24 patients with cervical cancer, 2 had stage IA2 disease, 19 had stage IB1 disease and 3 had stage IIA1 disease. Two patients had lymph node metastasis. The median tumor size on final pathology was 9 mm. No cancer cells were identified before or after hysterectomy in any patients.Conclusion: Total LRH with vaginal closure did not increase the propensity for tumor spillage in the peritoneal cavity.Keywords: cervical cancer, laparoscopy, radical hysterectomy, vaginal closure |
| first_indexed | 2024-12-13T01:39:52Z |
| format | Article |
| id | doaj.art-3f3aa8ceaaa24800bbaea5df02f7afbe |
| institution | Directory Open Access Journal |
| issn | 1179-1322 |
| language | English |
| last_indexed | 2024-12-13T01:39:52Z |
| publishDate | 2019-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Cancer Management and Research |
| spelling | doaj.art-3f3aa8ceaaa24800bbaea5df02f7afbe2022-12-22T00:03:46ZengDove Medical PressCancer Management and Research1179-13222019-07-01Volume 117015702047412Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational studyTanaka TMiyamoto STerada SKogata YSasaki HTsunetoh SYamada TOhmichi MTomohito Tanaka,1 Shunsuke Miyamoto,1 Shinichi Terada,1 Yuhei Kogata,1 Hiroshi Sasaki,1 Satoshi Tsunetoh,1 Takashi Yamada,2 Masahide Ohmichi11Department of Obstetrics and Gynecology, Osaka Medical College, Takatsuki, Japan; 2Department of Pathology, Osaka Medical College, Takatsuki, JapanPurpose: Although laparoscopic radical hysterectomy (LRH) has been performed for patients with cervical cancer because of its minimal invasiveness, a recent large prospective study showed that LRH was associated with a lower rate of disease-free survival and overall survival. However, the reason for these results is not apparent. The aim of this study was to evaluate the tumor spillage during LRH with vaginal closure without the use of a manipulator.Patients and methods: Twenty-four patients with cervical cancer underwent total LRH with vaginal closure. To evaluate the leakage of cancer cells during surgery, peritoneal cytology was performed before and after hysterectomy.Results: Among 24 patients with cervical cancer, 2 had stage IA2 disease, 19 had stage IB1 disease and 3 had stage IIA1 disease. Two patients had lymph node metastasis. The median tumor size on final pathology was 9 mm. No cancer cells were identified before or after hysterectomy in any patients.Conclusion: Total LRH with vaginal closure did not increase the propensity for tumor spillage in the peritoneal cavity.Keywords: cervical cancer, laparoscopy, radical hysterectomy, vaginal closurehttps://www.dovepress.com/intraperitoneal-cytology-after-laparoscopic-radical-hysterectomy-with--peer-reviewed-article-CMARcervical cancerlaparoscopyradical hysterectomyvaginal closure |
| spellingShingle | Tanaka T Miyamoto S Terada S Kogata Y Sasaki H Tsunetoh S Yamada T Ohmichi M Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study Cancer Management and Research cervical cancer laparoscopy radical hysterectomy vaginal closure |
| title | Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study |
| title_full | Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study |
| title_fullStr | Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study |
| title_full_unstemmed | Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study |
| title_short | Intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer: a retrospective observational study |
| title_sort | intraperitoneal cytology after laparoscopic radical hysterectomy with vaginal closure without the use of a manipulator for cervical cancer a retrospective observational study |
| topic | cervical cancer laparoscopy radical hysterectomy vaginal closure |
| url | https://www.dovepress.com/intraperitoneal-cytology-after-laparoscopic-radical-hysterectomy-with--peer-reviewed-article-CMAR |
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