Significance of MiRNA-34a and MiRNA-192 as a risk factor for nonalcoholic fatty liver disease

Significance of MiRNA-34a and MiRNA-192 as a risk factor for nonalcoholic fatty liver disease

Highlights ● NAFLD is deliberated a complicated health problem owing to its growing prevalence, complex pathogenesis, and difficulty to diagnose. ● It is crucial to find an efficient noninvasive and affordable biomarker for earlier identification and staging of NAFLD. ● Ultimate role of miRNA-34a in...

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Bibliographic Details
Main Authors: Halla M. Ragab, Wafaa M. Ezzat, Eman Mahmoud Hassan, Nabila Abd El Maksoud, Mie Afify, Mohamed D. E. Abd El-Maksoud, Wafaa Abd Elaziz
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Nonalcoholic fatty liver disease (NAFLD)
Gene expression
microRNAs (miRNAs)
MiRNA-34a
miRNA-192
Online Access:https://doi.org/10.1186/s43141-023-00467-z
Description
Summary:Highlights ● NAFLD is deliberated a complicated health problem owing to its growing prevalence, complex pathogenesis, and difficulty to diagnose. ● It is crucial to find an efficient noninvasive and affordable biomarker for earlier identification and staging of NAFLD. ● Ultimate role of miRNA-34a in lipid metabolism dysregulation may lead to NAFLD. ● MiRNA-34a and MiRNA-192 are broadly stated to play a role in the development of NAFLD and NASH.
ISSN:2090-5920

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