The use of sodium hyaluronate to treat upper limb disease: A review

The most common diseases of the upper limb are osteoarthritis (OA) of the joints of the hands, lateral epiconlitis, tendinitis of the shoulder muscles, adhesive capsulitis. OA of the shoulder and acromioclavicular joints is less common. The development of acute and subacute pain in the elbow and sho...

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Main Authors: Yulia S. Filatova, Mikhail V. Ilyin
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2023-07-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/551833/132657
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author Yulia S. Filatova
Mikhail V. Ilyin
author_facet Yulia S. Filatova
Mikhail V. Ilyin
author_sort Yulia S. Filatova
collection DOAJ
description The most common diseases of the upper limb are osteoarthritis (OA) of the joints of the hands, lateral epiconlitis, tendinitis of the shoulder muscles, adhesive capsulitis. OA of the shoulder and acromioclavicular joints is less common. The development of acute and subacute pain in the elbow and shoulder joints in the vast majority of cases is determined by the pathology of soft tissues: muscles, ligamentous apparatus and related synovial bags, making it difficult to diagnose. A clinical and radiological heterogeneity of OA of the joints of the hands is a very complex pathology for the study, and also to create a unified algorithms for therapy. Therapy nonsteroidal anti-inflammatory drugs are effective in the short term, but it has several side effects. Despite a variety of attempts at therapy with successful and unsuccessful outcome, the attention of researchers for several decades converted to the injection therapy with hyaluronic acid. The article presents the data of studies demonstrating the anti-inflammatory effect of hyaluronic acid in the treatment of OA, as well as the results of clinical trials and data system of meta-analysis demonstrating the effectiveness of intra-articular and extra-articular therapy tendinopathy of the upper limb. Most of the cited studies demonstrated the efficacy and good tolerance of 1% sodium hyaluronate. In the domestic market it is presented in the drug Flexotron Forte. The authors provide the results of the study results, demonstrating the efficacy and safety of using Flexotron Forte to clinical practice.
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spelling doaj.art-3f3ef4c94d3143d9ab5e1eb2c1fc0b212023-07-25T11:14:52Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422023-07-0195543844310.26442/00403660.2023.05.20227378301The use of sodium hyaluronate to treat upper limb disease: A reviewYulia S. Filatova0https://orcid.org/0000-0003-3024-9483Mikhail V. Ilyin1https://orcid.org/0000-0001-6278-374XYaroslavl State Medical UniversityYaroslavl State Medical UniversityThe most common diseases of the upper limb are osteoarthritis (OA) of the joints of the hands, lateral epiconlitis, tendinitis of the shoulder muscles, adhesive capsulitis. OA of the shoulder and acromioclavicular joints is less common. The development of acute and subacute pain in the elbow and shoulder joints in the vast majority of cases is determined by the pathology of soft tissues: muscles, ligamentous apparatus and related synovial bags, making it difficult to diagnose. A clinical and radiological heterogeneity of OA of the joints of the hands is a very complex pathology for the study, and also to create a unified algorithms for therapy. Therapy nonsteroidal anti-inflammatory drugs are effective in the short term, but it has several side effects. Despite a variety of attempts at therapy with successful and unsuccessful outcome, the attention of researchers for several decades converted to the injection therapy with hyaluronic acid. The article presents the data of studies demonstrating the anti-inflammatory effect of hyaluronic acid in the treatment of OA, as well as the results of clinical trials and data system of meta-analysis demonstrating the effectiveness of intra-articular and extra-articular therapy tendinopathy of the upper limb. Most of the cited studies demonstrated the efficacy and good tolerance of 1% sodium hyaluronate. In the domestic market it is presented in the drug Flexotron Forte. The authors provide the results of the study results, demonstrating the efficacy and safety of using Flexotron Forte to clinical practice.https://ter-arkhiv.ru/0040-3660/article/viewFile/551833/132657osteoarthritishyaluronic acidintra-articular administration of hyaluronic acid in osteoarthritis of the joints of the handstendencyepicondylitistendinit of the rotator cuffacromioclavicular osteoarthritisflextron forte
spellingShingle Yulia S. Filatova
Mikhail V. Ilyin
The use of sodium hyaluronate to treat upper limb disease: A review
Терапевтический архив
osteoarthritis
hyaluronic acid
intra-articular administration of hyaluronic acid in osteoarthritis of the joints of the hands
tendency
epicondylitis
tendinit of the rotator cuff
acromioclavicular osteoarthritis
flextron forte
title The use of sodium hyaluronate to treat upper limb disease: A review
title_full The use of sodium hyaluronate to treat upper limb disease: A review
title_fullStr The use of sodium hyaluronate to treat upper limb disease: A review
title_full_unstemmed The use of sodium hyaluronate to treat upper limb disease: A review
title_short The use of sodium hyaluronate to treat upper limb disease: A review
title_sort use of sodium hyaluronate to treat upper limb disease a review
topic osteoarthritis
hyaluronic acid
intra-articular administration of hyaluronic acid in osteoarthritis of the joints of the hands
tendency
epicondylitis
tendinit of the rotator cuff
acromioclavicular osteoarthritis
flextron forte
url https://ter-arkhiv.ru/0040-3660/article/viewFile/551833/132657
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