The Perioperative Effects of Statins in Non Cardiac Surgeries

Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery. Methods: A literature review was done on all English published articles till Febru...

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Bibliographic Details
Main Authors: Atieh Rezaeefar, Reza Shariat Moharari, Atabak Najafi, Mohammad Reza Khajavi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-11-01
Series:Archives of Anesthesia and Critical Care
Subjects:
Online Access:https://aacc.tums.ac.ir/index.php/aacc/article/view/30
Description
Summary:Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery. Methods: A literature review was done on all English published articles till February 2015 about this subject using pubmed. Then the reference list of relevant articles was reviewed for additional resources. Results: Current evidence shows that not only statins decrease perioperative morbidity and mortality in patients undergoing non cardiac surgery, but also they seem safe during perioperative period. Conclusion: A properly designed randomized control trial should be performed to assess the perioperative benefits of statins in non cardiac surgery.
ISSN:2423-5849