The Perioperative Effects of Statins in Non Cardiac Surgeries

Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery. Methods: A literature review was done on all English published articles till Febru...

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Main Authors: Atieh Rezaeefar, Reza Shariat Moharari, Atabak Najafi, Mohammad Reza Khajavi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-11-01
Series:Archives of Anesthesia and Critical Care
Subjects:
Online Access:https://aacc.tums.ac.ir/index.php/aacc/article/view/30
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author Atieh Rezaeefar
Reza Shariat Moharari
Atabak Najafi
Mohammad Reza Khajavi
author_facet Atieh Rezaeefar
Reza Shariat Moharari
Atabak Najafi
Mohammad Reza Khajavi
author_sort Atieh Rezaeefar
collection DOAJ
description Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery. Methods: A literature review was done on all English published articles till February 2015 about this subject using pubmed. Then the reference list of relevant articles was reviewed for additional resources. Results: Current evidence shows that not only statins decrease perioperative morbidity and mortality in patients undergoing non cardiac surgery, but also they seem safe during perioperative period. Conclusion: A properly designed randomized control trial should be performed to assess the perioperative benefits of statins in non cardiac surgery.
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spelling doaj.art-3f416b3ee8654eb993de8eb4d879bfab2022-12-22T00:27:53ZengTehran University of Medical SciencesArchives of Anesthesia and Critical Care2423-58492015-11-0114The Perioperative Effects of Statins in Non Cardiac SurgeriesAtieh Rezaeefar0Reza Shariat Moharari1Atabak Najafi2Mohammad Reza Khajavi3Department of Cardiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology and Critical Care, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology and Critical Care, Tehran University of Medical Sciences, Tehran, Iran.Department of Anesthesiology and Critical Care, Tehran University of Medical Sciences, Tehran, Iran.Background: Statins (3-Hydroxy-3-methylglutarylcoenzyme-A (HMG-CoA) reductase inhibitors) decrease cardiovascular mortality and morbidity. This article reviews the role of perioperative statins in non cardiac surgery. Methods: A literature review was done on all English published articles till February 2015 about this subject using pubmed. Then the reference list of relevant articles was reviewed for additional resources. Results: Current evidence shows that not only statins decrease perioperative morbidity and mortality in patients undergoing non cardiac surgery, but also they seem safe during perioperative period. Conclusion: A properly designed randomized control trial should be performed to assess the perioperative benefits of statins in non cardiac surgery.https://aacc.tums.ac.ir/index.php/aacc/article/view/30statinsnon cardiac surgeryperioperative periods
spellingShingle Atieh Rezaeefar
Reza Shariat Moharari
Atabak Najafi
Mohammad Reza Khajavi
The Perioperative Effects of Statins in Non Cardiac Surgeries
Archives of Anesthesia and Critical Care
statins
non cardiac surgery
perioperative periods
title The Perioperative Effects of Statins in Non Cardiac Surgeries
title_full The Perioperative Effects of Statins in Non Cardiac Surgeries
title_fullStr The Perioperative Effects of Statins in Non Cardiac Surgeries
title_full_unstemmed The Perioperative Effects of Statins in Non Cardiac Surgeries
title_short The Perioperative Effects of Statins in Non Cardiac Surgeries
title_sort perioperative effects of statins in non cardiac surgeries
topic statins
non cardiac surgery
perioperative periods
url https://aacc.tums.ac.ir/index.php/aacc/article/view/30
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