Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study

Abstract Background The present study aimed to assess variables associated to ICU-mortality among patients admitted to surgical intensive care unit in Ethiopia. Methods A Hospital-based retrospective follow-up study was conducted on all patients who were admitted to the surgical intensive care unit....

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Main Authors: Misgan Mulatie Zewudie, Debas Yaregal Melesse, Tesera Dereje Filatie, Mulualem Endeshaw Zeleke
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-023-02230-w
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author Misgan Mulatie Zewudie
Debas Yaregal Melesse
Tesera Dereje Filatie
Mulualem Endeshaw Zeleke
author_facet Misgan Mulatie Zewudie
Debas Yaregal Melesse
Tesera Dereje Filatie
Mulualem Endeshaw Zeleke
author_sort Misgan Mulatie Zewudie
collection DOAJ
description Abstract Background The present study aimed to assess variables associated to ICU-mortality among patients admitted to surgical intensive care unit in Ethiopia. Methods A Hospital-based retrospective follow-up study was conducted on all patients who were admitted to the surgical intensive care unit. Data were extracted from patients’ charts with a pretested data extraction tool, entered into Epi-data 4.6.0, and analyzed with STATA- 14. Bivariate and multivariate Cox proportional hazards regression models were fitted. Results Of the total study participants (388), 148 (38.1%) patients admitted to the surgical intensive care unit died during the follow-up period with a median survival time of 11 days. Potassium level < 3.5 mmol/L (adjusted hazard ratio ( AHR): 3.46, 95% CI (1.83 6.55), potassium level > 5.0 mmol/L (AHR:2.41, 95% CI (1.29–4.51), hypoxia (AHR:1.66, 95% CI (1.10–2.48), Glasgow Coma Scale (GCS) score < 9 (AHR: 4.06, 95% CI (1.51–10.89), mechanical ventilation (AHR:12, 95%CI (3–45), absence of thromboprophylaxis (AHR:10.8,95% CI (6.04–19.29), absence of enteral feeding (AHR:3.56, 95% CI (2.20–5.78) were variables associated with ICU-mortality among patients admitted to surgical intensive care unit. Conclusions The overall ICU-mortality of patients admitted to our surgical intensive care unit was higher compared to patients admitted to similar intensive care unit in developed countries. The variables associated to ICU-mortality among patients admitted to surgical intensive care unit were abnormal serum potassium level, lower GCS score, mechanical support, hypoxia, absence of thromboprophylaxis, and enteral feeding.
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spelling doaj.art-3f47b6f75e284e9cb3abfc0d0687b9142023-11-26T14:02:59ZengBMCBMC Anesthesiology1471-22532023-08-012311910.1186/s12871-023-02230-wVariables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational studyMisgan Mulatie Zewudie0Debas Yaregal Melesse1Tesera Dereje Filatie2Mulualem Endeshaw Zeleke3Department of Anesthesia, College of Medicine and Health Sciences, Injibara UniversityDepartment of Anesthesia, College of Medicine and Health Science, University of GondarDepartment of Anesthesia, College of Medicine and Health Science, University of GondarDepartment of Anesthesia, College of Medicine and Health Science, University of GondarAbstract Background The present study aimed to assess variables associated to ICU-mortality among patients admitted to surgical intensive care unit in Ethiopia. Methods A Hospital-based retrospective follow-up study was conducted on all patients who were admitted to the surgical intensive care unit. Data were extracted from patients’ charts with a pretested data extraction tool, entered into Epi-data 4.6.0, and analyzed with STATA- 14. Bivariate and multivariate Cox proportional hazards regression models were fitted. Results Of the total study participants (388), 148 (38.1%) patients admitted to the surgical intensive care unit died during the follow-up period with a median survival time of 11 days. Potassium level < 3.5 mmol/L (adjusted hazard ratio ( AHR): 3.46, 95% CI (1.83 6.55), potassium level > 5.0 mmol/L (AHR:2.41, 95% CI (1.29–4.51), hypoxia (AHR:1.66, 95% CI (1.10–2.48), Glasgow Coma Scale (GCS) score < 9 (AHR: 4.06, 95% CI (1.51–10.89), mechanical ventilation (AHR:12, 95%CI (3–45), absence of thromboprophylaxis (AHR:10.8,95% CI (6.04–19.29), absence of enteral feeding (AHR:3.56, 95% CI (2.20–5.78) were variables associated with ICU-mortality among patients admitted to surgical intensive care unit. Conclusions The overall ICU-mortality of patients admitted to our surgical intensive care unit was higher compared to patients admitted to similar intensive care unit in developed countries. The variables associated to ICU-mortality among patients admitted to surgical intensive care unit were abnormal serum potassium level, lower GCS score, mechanical support, hypoxia, absence of thromboprophylaxis, and enteral feeding.https://doi.org/10.1186/s12871-023-02230-wIncidenceIntensive care unitMortalityPredictorsSurgical
spellingShingle Misgan Mulatie Zewudie
Debas Yaregal Melesse
Tesera Dereje Filatie
Mulualem Endeshaw Zeleke
Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
BMC Anesthesiology
Incidence
Intensive care unit
Mortality
Predictors
Surgical
title Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
title_full Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
title_fullStr Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
title_full_unstemmed Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
title_short Variables associated to intensive care unit (ICU)-mortality among patients admitted to surgical intensive care unit in Ethiopia: a retrospective observational study
title_sort variables associated to intensive care unit icu mortality among patients admitted to surgical intensive care unit in ethiopia a retrospective observational study
topic Incidence
Intensive care unit
Mortality
Predictors
Surgical
url https://doi.org/10.1186/s12871-023-02230-w
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AT teseraderejefilatie variablesassociatedtointensivecareuniticumortalityamongpatientsadmittedtosurgicalintensivecareunitinethiopiaaretrospectiveobservationalstudy
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