Identification of immunodominant CD4-restricted epitopes co-located with antibody binding sites in individuals vaccinated with ALVAC-HIV and AIDSVAX B/E.
We performed fine epitope mapping of the CD4+ responses in the ALVAC-HIV-AIDSVAX B/E prime-boost regimen in the Thai Phase III trial (RV144). Non-transformed Env-specific T cell lines established from RV144 vaccinees were used to determine the fine epitope mapping of the V2 and C1 responses and the...
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Bibliographic Details
| Main Authors: |
Silvia Ratto-Kim,
Mark S de Souza,
Jeffrey R Currier,
Nicos Karasavvas,
John Sidney,
Morgane Rolland,
Anais Valencia-Micolta,
Sirinan Madnote,
Alessandro Sette,
Sorachai Nitayaphan,
Punnee Pitisuttuthum,
Jaranit Kaewkungwal,
Supachai Rerks-Ngarm,
Robert O'Connell,
Nelson Michael,
Merlin L Robb,
Mary Marovich,
Jerome H Kim |
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| Format: | Article
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| Language: | English |
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| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE
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| Online Access: | http://europepmc.org/articles/PMC4321833?pdf=render
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