A Hydrazine–Hydrazone Adamantine Compound Shows Antimycobacterial Activity and Is a Probable Inhibitor of MmpL3

A Hydrazine–Hydrazone Adamantine Compound Shows Antimycobacterial Activity and Is a Probable Inhibitor of MmpL3

Tuberculosis remains an important cause of morbidity and mortality throughout the world. Notably, an important number of multi drug resistant cases is an increasing concern. This problem points to an urgent need for novel compounds with antimycobacterial properties and to improve existing therapies....

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Bibliographic Details
Main Authors: Julien Briffotaux, Yanji Xu, Wei Huang, Zhen Hui, Xiao Wang, Brigitte Gicquel, Shengyuan Liu
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
tuberculosis
MmpL3
drug screening
small molecules
drug resistance
Online Access:https://www.mdpi.com/1420-3049/27/20/7130

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