Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron
Introduction: Amoxicillin is one of the most important groups of pharmaceuticals that benefits humans and animals. However, antibiotics excertion in wastewaters and environment have emerged as a serious risk to the biotic environment, and their toxic effects can harm the organisms. Iron-based metall...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Shahid Sadoughi University of Medical Sciences
2016-03-01
|
| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| Subjects: | |
| Online Access: | http://jssu.ssu.ac.ir/browse.php?a_code=A-10-2411-1&slc_lang=en&sid=1 |
| _version_ | 1819135436654641152 |
|---|---|
| author | AR Yazdanbakhsh M Rafiee H Daraei H Kamali |
| author_facet | AR Yazdanbakhsh M Rafiee H Daraei H Kamali |
| author_sort | AR Yazdanbakhsh |
| collection | DOAJ |
| description | Introduction: Amoxicillin is one of the most important groups of pharmaceuticals that benefits humans and animals. However, antibiotics excertion in wastewaters and environment have emerged as a serious risk to the biotic environment, and their toxic effects can harm the organisms. Iron-based metallic nanoparticles have received special attention in regard with remediation of groundwater contaminants. In the typical nZVI-based bimetallic particle system, Fe acts as the reducing agent. Thus, the present study aimed to evaluate the synthesis and characteristics of nZVI in regard with degrading AMX.
Methods: In this study, nZVI nanoparticles were synthesized using the liquid-phase reduction method by EDTA as a stabilizer material. Structure and properties of nanoparticles were characterized by BET, SEM, XRD and EDX analysis. A multi-variate analysis was applied using a response surface methodology (RSM) in order to develop a quadratic model as a functional relationship between AMX removal efficiency and independent variables ( initial pH values, dosage of nZVI, contact time and amoxicillin concentration). The four independent variables of solution pH (2–10), AMX concentration (5-45mg/l), contact time (5-85 min) and nanoparticles dose (0.25 – 1.25 g) were transformed to the coded values.
Results: The study results demonstrated that more than 69 % of AMX was removed by nZVI. The optimal AMX removal conditions using nZVI were found as 1.25 g of nZVI, pH 4, contact time of 80 min and concentration of 30 mg/l.
Conclusions: The ability of nZVI in degradation of AMX revealed that these materials can serve as a potential nano material with respect to the environmental remediation. |
| first_indexed | 2024-12-22T10:19:03Z |
| format | Article |
| id | doaj.art-3f50084129124c1fb9d4fd04ab50fcaa |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-12-22T10:19:03Z |
| publishDate | 2016-03-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-3f50084129124c1fb9d4fd04ab50fcaa2022-12-21T18:29:40ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332016-03-01231211551168Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent IronAR Yazdanbakhsh0M Rafiee1H Daraei2H Kamali3 Department of Environmental Health Engineering Department of Environmental Health Engineering Students research office School of Medicine Introduction: Amoxicillin is one of the most important groups of pharmaceuticals that benefits humans and animals. However, antibiotics excertion in wastewaters and environment have emerged as a serious risk to the biotic environment, and their toxic effects can harm the organisms. Iron-based metallic nanoparticles have received special attention in regard with remediation of groundwater contaminants. In the typical nZVI-based bimetallic particle system, Fe acts as the reducing agent. Thus, the present study aimed to evaluate the synthesis and characteristics of nZVI in regard with degrading AMX. Methods: In this study, nZVI nanoparticles were synthesized using the liquid-phase reduction method by EDTA as a stabilizer material. Structure and properties of nanoparticles were characterized by BET, SEM, XRD and EDX analysis. A multi-variate analysis was applied using a response surface methodology (RSM) in order to develop a quadratic model as a functional relationship between AMX removal efficiency and independent variables ( initial pH values, dosage of nZVI, contact time and amoxicillin concentration). The four independent variables of solution pH (2–10), AMX concentration (5-45mg/l), contact time (5-85 min) and nanoparticles dose (0.25 – 1.25 g) were transformed to the coded values. Results: The study results demonstrated that more than 69 % of AMX was removed by nZVI. The optimal AMX removal conditions using nZVI were found as 1.25 g of nZVI, pH 4, contact time of 80 min and concentration of 30 mg/l. Conclusions: The ability of nZVI in degradation of AMX revealed that these materials can serve as a potential nano material with respect to the environmental remediation.http://jssu.ssu.ac.ir/browse.php?a_code=A-10-2411-1&slc_lang=en&sid=1Amoxicillin Nanoparticles NZVI Stabilize Synthesize |
| spellingShingle | AR Yazdanbakhsh M Rafiee H Daraei H Kamali Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Amoxicillin Nanoparticles NZVI Stabilize Synthesize |
| title | Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron |
| title_full | Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron |
| title_fullStr | Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron |
| title_full_unstemmed | Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron |
| title_short | Amoxicillin Oxidative Degradation Synthesized by Nano Zero Valent Iron |
| title_sort | amoxicillin oxidative degradation synthesized by nano zero valent iron |
| topic | Amoxicillin Nanoparticles NZVI Stabilize Synthesize |
| url | http://jssu.ssu.ac.ir/browse.php?a_code=A-10-2411-1&slc_lang=en&sid=1 |
| work_keys_str_mv | AT aryazdanbakhsh amoxicillinoxidativedegradationsynthesizedbynanozerovalentiron AT mrafiee amoxicillinoxidativedegradationsynthesizedbynanozerovalentiron AT hdaraei amoxicillinoxidativedegradationsynthesizedbynanozerovalentiron AT hkamali amoxicillinoxidativedegradationsynthesizedbynanozerovalentiron |