Inhalable Vaccines: Can They Help Control Pandemics?
The emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to ne...
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Format: | Article |
Language: | English |
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MDPI AG
2022-08-01
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Series: | Vaccines |
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Online Access: | https://www.mdpi.com/2076-393X/10/8/1309 |
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author | Vivek P. Chavda Lalitkumar K. Vora Vasso Apostolopoulos |
author_facet | Vivek P. Chavda Lalitkumar K. Vora Vasso Apostolopoulos |
author_sort | Vivek P. Chavda |
collection | DOAJ |
description | The emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to new viral variants. These emerging variants pose a challenge to existing COVID-19 management strategies and vaccine efficacy. Interruption of viral spread is required as the merging variants pose higher transmissibility than the previous ones. To achieve this, local protection of the respiratory tract with immunity is essential. Here, we advocate the use of pulmonary/inhalable vaccines to achieve this goal. |
first_indexed | 2024-03-09T09:47:39Z |
format | Article |
id | doaj.art-3f53ed16b5f043878ae3fd08db0075e8 |
institution | Directory Open Access Journal |
issn | 2076-393X |
language | English |
last_indexed | 2024-03-09T09:47:39Z |
publishDate | 2022-08-01 |
publisher | MDPI AG |
record_format | Article |
series | Vaccines |
spelling | doaj.art-3f53ed16b5f043878ae3fd08db0075e82023-12-02T00:25:38ZengMDPI AGVaccines2076-393X2022-08-01108130910.3390/vaccines10081309Inhalable Vaccines: Can They Help Control Pandemics?Vivek P. Chavda0Lalitkumar K. Vora1Vasso Apostolopoulos2Department of Pharmaceutics and Pharmaceutical Technology, L M College of Pharmacy, Ahmedabad 380009, Gujarat, IndiaSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UKImmunology and Translational Research Group, Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, AustraliaThe emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to new viral variants. These emerging variants pose a challenge to existing COVID-19 management strategies and vaccine efficacy. Interruption of viral spread is required as the merging variants pose higher transmissibility than the previous ones. To achieve this, local protection of the respiratory tract with immunity is essential. Here, we advocate the use of pulmonary/inhalable vaccines to achieve this goal.https://www.mdpi.com/2076-393X/10/8/1309pulmonary vaccineintranasal vaccineinhalable vaccineSARS-CoV-2COVID-19vaccine |
spellingShingle | Vivek P. Chavda Lalitkumar K. Vora Vasso Apostolopoulos Inhalable Vaccines: Can They Help Control Pandemics? Vaccines pulmonary vaccine intranasal vaccine inhalable vaccine SARS-CoV-2 COVID-19 vaccine |
title | Inhalable Vaccines: Can They Help Control Pandemics? |
title_full | Inhalable Vaccines: Can They Help Control Pandemics? |
title_fullStr | Inhalable Vaccines: Can They Help Control Pandemics? |
title_full_unstemmed | Inhalable Vaccines: Can They Help Control Pandemics? |
title_short | Inhalable Vaccines: Can They Help Control Pandemics? |
title_sort | inhalable vaccines can they help control pandemics |
topic | pulmonary vaccine intranasal vaccine inhalable vaccine SARS-CoV-2 COVID-19 vaccine |
url | https://www.mdpi.com/2076-393X/10/8/1309 |
work_keys_str_mv | AT vivekpchavda inhalablevaccinescantheyhelpcontrolpandemics AT lalitkumarkvora inhalablevaccinescantheyhelpcontrolpandemics AT vassoapostolopoulos inhalablevaccinescantheyhelpcontrolpandemics |