Inhalable Vaccines: Can They Help Control Pandemics?

The emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to ne...

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Main Authors: Vivek P. Chavda, Lalitkumar K. Vora, Vasso Apostolopoulos
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/8/1309
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author Vivek P. Chavda
Lalitkumar K. Vora
Vasso Apostolopoulos
author_facet Vivek P. Chavda
Lalitkumar K. Vora
Vasso Apostolopoulos
author_sort Vivek P. Chavda
collection DOAJ
description The emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to new viral variants. These emerging variants pose a challenge to existing COVID-19 management strategies and vaccine efficacy. Interruption of viral spread is required as the merging variants pose higher transmissibility than the previous ones. To achieve this, local protection of the respiratory tract with immunity is essential. Here, we advocate the use of pulmonary/inhalable vaccines to achieve this goal.
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spelling doaj.art-3f53ed16b5f043878ae3fd08db0075e82023-12-02T00:25:38ZengMDPI AGVaccines2076-393X2022-08-01108130910.3390/vaccines10081309Inhalable Vaccines: Can They Help Control Pandemics?Vivek P. Chavda0Lalitkumar K. Vora1Vasso Apostolopoulos2Department of Pharmaceutics and Pharmaceutical Technology, L M College of Pharmacy, Ahmedabad 380009, Gujarat, IndiaSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UKImmunology and Translational Research Group, Institute for Health and Sport, Victoria University, Melbourne, VIC 3030, AustraliaThe emergence of a new coronavirus presents a huge risk to public health worldwide and has spread widely amongst the human population. Since its emergence, the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is frequently evolving by mutation and genetic recombination to give rise to new viral variants. These emerging variants pose a challenge to existing COVID-19 management strategies and vaccine efficacy. Interruption of viral spread is required as the merging variants pose higher transmissibility than the previous ones. To achieve this, local protection of the respiratory tract with immunity is essential. Here, we advocate the use of pulmonary/inhalable vaccines to achieve this goal.https://www.mdpi.com/2076-393X/10/8/1309pulmonary vaccineintranasal vaccineinhalable vaccineSARS-CoV-2COVID-19vaccine
spellingShingle Vivek P. Chavda
Lalitkumar K. Vora
Vasso Apostolopoulos
Inhalable Vaccines: Can They Help Control Pandemics?
Vaccines
pulmonary vaccine
intranasal vaccine
inhalable vaccine
SARS-CoV-2
COVID-19
vaccine
title Inhalable Vaccines: Can They Help Control Pandemics?
title_full Inhalable Vaccines: Can They Help Control Pandemics?
title_fullStr Inhalable Vaccines: Can They Help Control Pandemics?
title_full_unstemmed Inhalable Vaccines: Can They Help Control Pandemics?
title_short Inhalable Vaccines: Can They Help Control Pandemics?
title_sort inhalable vaccines can they help control pandemics
topic pulmonary vaccine
intranasal vaccine
inhalable vaccine
SARS-CoV-2
COVID-19
vaccine
url https://www.mdpi.com/2076-393X/10/8/1309
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AT vassoapostolopoulos inhalablevaccinescantheyhelpcontrolpandemics