Recent advances in targeting protein kinases and pseudokinases in cancer biology
Kinases still remain the most favorable members of the druggable genome, and there are an increasing number of kinase inhibitors approved by the FDA to treat a variety of cancers. Here, we summarize recent developments in targeting kinases and pseudokinases with some examples. Targeting the cell cyc...
Autores principales: | Kristina Riegel, Parthiban Vijayarangakannan, Petros Kechagioglou, Katarzyna Bogucka, Krishnaraj Rajalingam |
---|---|
Formato: | Artículo |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022-07-01
|
Colección: | Frontiers in Cell and Developmental Biology |
Materias: | |
Acceso en línea: | https://www.frontiersin.org/articles/10.3389/fcell.2022.942500/full |
Ejemplares similares
-
Targeting CRAF kinase in anti-cancer therapy: progress and opportunities
por: Penglei Wang, et al.
Publicado: (2023-12-01) -
Unveiling the domain-specific and RAS isoform-specific details of BRAF kinase regulation
por: Tarah Elizabeth Trebino, et al.
Publicado: (2023-12-01) -
CDK4/6 and MAPK—Crosstalk as Opportunity for Cancer Treatment
por: Lisa Scheiblecker, et al.
Publicado: (2020-11-01) -
Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition
por: Mengqian Chen, et al.
Publicado: (2019-11-01) -
Pharmacological approaches to understanding protein kinase signaling networks
por: Elloise H. Stephenson, et al.
Publicado: (2023-12-01)