The neuroprotective effect of dexmedetomidine and its mechanism

The neuroprotective effect of dexmedetomidine and its mechanism

Dexmedetomidine (DEX) is a highly selective α2 receptor agonist that is routinely used in the clinic for sedation and anesthesia. Recently, an increasing number of studies have shown that DEX has a protective effect against brain injury caused by traumatic brain injury (TBI), subarachnoid hemorrhage...

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Bibliographic Details
Main Authors: Yijun Hu, Hong Zhou, Huanxin Zhang, Yunlong Sui, Zhen Zhang, Yuntao Zou, Kunquan Li, Yunyi Zhao, Jiangbo Xie, Lunzhong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
dexmedetomidine
neuroprotective
inflammatory response
cell apoptosis
blood-brain barrier
cell structure protection
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.965661/full

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