Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure
Takaaki Furihata et al. report a new mouse model with heart-specific deletion of the mitochondrial protein, mitoNEET. Their results suggest that loss of mitoNEET expression may contribute to age-associated heart failure in older adults.
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-01-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-01675-4 |
| _version_ | 1818400741363023872 |
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| author | Takaaki Furihata Shingo Takada Naoya Kakutani Satoshi Maekawa Masaya Tsuda Junichi Matsumoto Wataru Mizushima Arata Fukushima Takashi Yokota Nobuyuki Enzan Shouji Matsushima Haruka Handa Yoshizuki Fumoto Junko Nio-Kobayashi Toshihiko Iwanaga Shinya Tanaka Hiroyuki Tsutsui Hisataka Sabe Shintaro Kinugawa |
| author_facet | Takaaki Furihata Shingo Takada Naoya Kakutani Satoshi Maekawa Masaya Tsuda Junichi Matsumoto Wataru Mizushima Arata Fukushima Takashi Yokota Nobuyuki Enzan Shouji Matsushima Haruka Handa Yoshizuki Fumoto Junko Nio-Kobayashi Toshihiko Iwanaga Shinya Tanaka Hiroyuki Tsutsui Hisataka Sabe Shintaro Kinugawa |
| author_sort | Takaaki Furihata |
| collection | DOAJ |
| description | Takaaki Furihata et al. report a new mouse model with heart-specific deletion of the mitochondrial protein, mitoNEET. Their results suggest that loss of mitoNEET expression may contribute to age-associated heart failure in older adults. |
| first_indexed | 2024-12-14T07:41:23Z |
| format | Article |
| id | doaj.art-3f63983eae254d919bb87225d2d4c10c |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-14T07:41:23Z |
| publishDate | 2021-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-3f63983eae254d919bb87225d2d4c10c2022-12-21T23:11:01ZengNature PortfolioCommunications Biology2399-36422021-01-014111110.1038/s42003-021-01675-4Cardiac-specific loss of mitoNEET expression is linked with age-related heart failureTakaaki Furihata0Shingo Takada1Naoya Kakutani2Satoshi Maekawa3Masaya Tsuda4Junichi Matsumoto5Wataru Mizushima6Arata Fukushima7Takashi Yokota8Nobuyuki Enzan9Shouji Matsushima10Haruka Handa11Yoshizuki Fumoto12Junko Nio-Kobayashi13Toshihiko Iwanaga14Shinya Tanaka15Hiroyuki Tsutsui16Hisataka Sabe17Shintaro Kinugawa18Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Kyushu University Graduate School of Medical SciencesDepartment of Cardiovascular Medicine, Kyushu University Graduate School of Medical SciencesDepartment of Molecular Biology, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Molecular Biology, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityLaboratory of Histology and Cytology, Department of Anatomy, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityLaboratory of Histology and Cytology, Department of Anatomy, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cancer Pathology, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Kyushu University Graduate School of Medical SciencesDepartment of Molecular Biology, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityDepartment of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido UniversityTakaaki Furihata et al. report a new mouse model with heart-specific deletion of the mitochondrial protein, mitoNEET. Their results suggest that loss of mitoNEET expression may contribute to age-associated heart failure in older adults.https://doi.org/10.1038/s42003-021-01675-4 |
| spellingShingle | Takaaki Furihata Shingo Takada Naoya Kakutani Satoshi Maekawa Masaya Tsuda Junichi Matsumoto Wataru Mizushima Arata Fukushima Takashi Yokota Nobuyuki Enzan Shouji Matsushima Haruka Handa Yoshizuki Fumoto Junko Nio-Kobayashi Toshihiko Iwanaga Shinya Tanaka Hiroyuki Tsutsui Hisataka Sabe Shintaro Kinugawa Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure Communications Biology |
| title | Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure |
| title_full | Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure |
| title_fullStr | Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure |
| title_full_unstemmed | Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure |
| title_short | Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure |
| title_sort | cardiac specific loss of mitoneet expression is linked with age related heart failure |
| url | https://doi.org/10.1038/s42003-021-01675-4 |
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