Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma

Inactivation of tumor suppressor TAp63 by hepatitis B virus X protein in hepatocellular carcinoma

Abstract. Background:. The hepatitis B virus X (HBx) protein plays a critical role in the initiation and progression of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC). In the early stage of the disease, HBx facilitates tumor onset by inactivating the tumor suppressor p53. The p53-...

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Bibliographic Details
Main Authors: Bangxiang Xie, Qian Hao, Xiang Zhou, Dexi Chen, Yuanyuan Ji
Format: Article
Language:English
Published: Wolters Kluwer 2022-07-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002283

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