Optimization of Neferine Purification Based on Response Surface Methodology and Its Anti-Metastasis Mechanism on HepG2 Cells

Optimization of Neferine Purification Based on Response Surface Methodology and Its Anti-Metastasis Mechanism on HepG2 Cells

Liver cancer continues to be a focus of scientific research due to its low five-year survival rate. One of its main core issues is the high metastasis of cells, for which there is no effective treatment. Neferine was originally isolated from <i>Plumula nelumbinis</i> and demonstrated to...

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Bibliographic Details
Main Authors: Xinzhu Wang, Zhenhuan Wei, Po Hu, Weibo Xia, Zhixin Liao, Israa Assani, Guangming Yang, Yang Pan
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
Neferine
response surface methodology (RSM)
HepG2
migration and invasion
RhoA
Online Access:https://www.mdpi.com/1420-3049/28/13/5086

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