The rapid developments of membrane protein structure biology over the last two decades
Membrane protein research has flourished in the past 20 years. Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized the field. The next decade promises great pro...
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | BMC Biology |
| Online Access: | https://doi.org/10.1186/s12915-023-01795-9 |
| _version_ | 1797371133831413760 |
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| author | Lan Guan |
| author_facet | Lan Guan |
| author_sort | Lan Guan |
| collection | DOAJ |
| description | Membrane protein research has flourished in the past 20 years. Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized the field. The next decade promises great progress in understanding the critical roles of membrane transporters in health and disease and in the applications of novel drug design and development. |
| first_indexed | 2024-03-08T18:15:24Z |
| format | Article |
| id | doaj.art-3f6c047cdc1041e89a0329bef2e2a0e2 |
| institution | Directory Open Access Journal |
| issn | 1741-7007 |
| language | English |
| last_indexed | 2024-03-08T18:15:24Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Biology |
| spelling | doaj.art-3f6c047cdc1041e89a0329bef2e2a0e22023-12-31T12:15:57ZengBMCBMC Biology1741-70072023-12-012111410.1186/s12915-023-01795-9The rapid developments of membrane protein structure biology over the last two decadesLan Guan0Department of Cell Physiology and Molecular Biophysics, Center for Membrane Protein Research, School of Medicine, Texas Tech University Health Sciences CenterMembrane protein research has flourished in the past 20 years. Exciting technological innovations in structural biology, including cryoEM single-particle analysis and AI-based protein structure prediction, such as AlphaFold 2, have largely revolutionized the field. The next decade promises great progress in understanding the critical roles of membrane transporters in health and disease and in the applications of novel drug design and development.https://doi.org/10.1186/s12915-023-01795-9 |
| spellingShingle | Lan Guan The rapid developments of membrane protein structure biology over the last two decades BMC Biology |
| title | The rapid developments of membrane protein structure biology over the last two decades |
| title_full | The rapid developments of membrane protein structure biology over the last two decades |
| title_fullStr | The rapid developments of membrane protein structure biology over the last two decades |
| title_full_unstemmed | The rapid developments of membrane protein structure biology over the last two decades |
| title_short | The rapid developments of membrane protein structure biology over the last two decades |
| title_sort | rapid developments of membrane protein structure biology over the last two decades |
| url | https://doi.org/10.1186/s12915-023-01795-9 |
| work_keys_str_mv | AT languan therapiddevelopmentsofmembraneproteinstructurebiologyoverthelasttwodecades AT languan rapiddevelopmentsofmembraneproteinstructurebiologyoverthelasttwodecades |