Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion
The time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, a...
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Format: | Article |
Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2006-12-01
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Series: | Общая реаниматология |
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Online Access: | https://www.reanimatology.com/rmt/article/view/1361 |
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author | V. T. Dolgikh F. I. Razgonov L. G. Shikunova |
author_facet | V. T. Dolgikh F. I. Razgonov L. G. Shikunova |
author_sort | V. T. Dolgikh |
collection | DOAJ |
description | The time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, and 30) in the rate of lipoprotein processes and corresponding changes in the content of lipid hydroperoxides and Schiff s bases. Activation of lipid peroxidation processes occurred with deficiency of bioantioxidants and with inhibition of enzymes that made antiradical and antiperoxide protection of cardiomyocytes.acute fatal hemorrhage; resuscitation; heart; lipid peroxidation |
first_indexed | 2024-04-10T01:31:22Z |
format | Article |
id | doaj.art-3f6c964f943d424e8908a1a796d6be3b |
institution | Directory Open Access Journal |
issn | 1813-9779 2411-7110 |
language | English |
last_indexed | 2024-04-10T01:31:22Z |
publishDate | 2006-12-01 |
publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
record_format | Article |
series | Общая реаниматология |
spelling | doaj.art-3f6c964f943d424e8908a1a796d6be3b2023-03-13T09:32:46ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-12-0126505410.15360/1813-9779-2006-6-50-541361Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac LesionV. T. Dolgikh0F. I. Razgonov1L. G. Shikunova2Омская государственная медицинская академия (кафедра патофизиологии, кафедра военной и экстремальной медицины)Омская государственная медицинская академия (кафедра патофизиологии, кафедра военной и экстремальной медицины)ГУ НИИ общей реаниматологии РАМН, МоскваThe time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, and 30) in the rate of lipoprotein processes and corresponding changes in the content of lipid hydroperoxides and Schiff s bases. Activation of lipid peroxidation processes occurred with deficiency of bioantioxidants and with inhibition of enzymes that made antiradical and antiperoxide protection of cardiomyocytes.acute fatal hemorrhage; resuscitation; heart; lipid peroxidationhttps://www.reanimatology.com/rmt/article/view/1361острая смертельная кровопотеряреанимациясердцеперекисное окисление липидов |
spellingShingle | V. T. Dolgikh F. I. Razgonov L. G. Shikunova Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion Общая реаниматология острая смертельная кровопотеря реанимация сердце перекисное окисление липидов |
title | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
title_full | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
title_fullStr | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
title_full_unstemmed | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
title_short | Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion |
title_sort | acute fatal hemorrhage induced activation of lipid peroxidation processes and cardiac lesion |
topic | острая смертельная кровопотеря реанимация сердце перекисное окисление липидов |
url | https://www.reanimatology.com/rmt/article/view/1361 |
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