Effects of C1-INH Treatment on Neurobehavioral Sequelae and Late Seizures After Traumatic Brain Injury in a Mouse Model of Controlled Cortical Impact

Effects of C1-INH Treatment on Neurobehavioral Sequelae and Late Seizures After Traumatic Brain Injury in a Mouse Model of Controlled Cortical Impact

C1 human-derived C1 esterase inhibitor (C1-INH) is a U.S. Food and Drig Administration?approved drug with anti-inflammatory actions. In the present study, we investigated the therapeutic effects of C1-INH on acute and chronic neurobehavioral outcomes and on seizures in the chronic stage in a mouse t...

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Bibliographic Details
Main Authors: Min Chen, Quang M. Tieng, Jiaxin Du, Stephen R. Edwards, Dhiraj Maskey, Emil Peshtenski, David Reutens
Format: Article
Language:English
Published: Mary Ann Liebert 2023-03-01
Series:Neurotrauma Reports
Subjects:
C1-INH, epileptogenesis
neurobehavioral sequelae
traumatic brain injury
Online Access:https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0011

Internet

https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0011

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