Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations
We report a case of a fibromyalgia (FM) patient with an history of brain-cancer presenting signs and symptoms of gadolinium toxicity following repeated administrations of a macrocyclic contrast agent, Gadovist. In the present report, we provide evidence supporting the hypothesis of a causal relation...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-05-01
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| Series: | Radiology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320300431 |
| _version_ | 1831758432581976064 |
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| author | Silvia Maria Lattanzio, PhD Francesca Imbesi, MD |
| author_facet | Silvia Maria Lattanzio, PhD Francesca Imbesi, MD |
| author_sort | Silvia Maria Lattanzio, PhD |
| collection | DOAJ |
| description | We report a case of a fibromyalgia (FM) patient with an history of brain-cancer presenting signs and symptoms of gadolinium toxicity following repeated administrations of a macrocyclic contrast agent, Gadovist. In the present report, we provide evidence supporting the hypothesis of a causal relationship linking gadolinium deposition to a clinical manifestation of disease, namely fibromyalgia. We unravel a role for gadolinium in the still unknown etiology of fibromyalgia as a metal toxicity disorder. Contrast agents are routinely administered in a clinical context. It is thus possible that the patients are mistakenly believed to show complaint of their primary disease, whereas, in some instances, their symptoms are associated with gadolinium deposition. Keywords: Gadolinium deposition, Fibromyalgia syndrome, Chronic pain, Toxicity, Contrast agents, Magnetic resonance imaging |
| first_indexed | 2024-12-22T00:49:35Z |
| format | Article |
| id | doaj.art-3f6fe915870d408a91aa9ed167619b85 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-22T00:49:35Z |
| publishDate | 2020-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-3f6fe915870d408a91aa9ed167619b852022-12-21T18:44:28ZengElsevierRadiology Case Reports1930-04332020-05-01155534541Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinationsSilvia Maria Lattanzio, PhD0Francesca Imbesi, MD1Department of Biomedical Sciences, University of Padova, Via Marzolo 3, 35131, Padova, Italy; Corresponding author.Neurological Department, ASST Grande Ospedale Metropolitano Niguarda, Milano, ItalyWe report a case of a fibromyalgia (FM) patient with an history of brain-cancer presenting signs and symptoms of gadolinium toxicity following repeated administrations of a macrocyclic contrast agent, Gadovist. In the present report, we provide evidence supporting the hypothesis of a causal relationship linking gadolinium deposition to a clinical manifestation of disease, namely fibromyalgia. We unravel a role for gadolinium in the still unknown etiology of fibromyalgia as a metal toxicity disorder. Contrast agents are routinely administered in a clinical context. It is thus possible that the patients are mistakenly believed to show complaint of their primary disease, whereas, in some instances, their symptoms are associated with gadolinium deposition. Keywords: Gadolinium deposition, Fibromyalgia syndrome, Chronic pain, Toxicity, Contrast agents, Magnetic resonance imaginghttp://www.sciencedirect.com/science/article/pii/S1930043320300431 |
| spellingShingle | Silvia Maria Lattanzio, PhD Francesca Imbesi, MD Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations Radiology Case Reports |
| title | Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations |
| title_full | Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations |
| title_fullStr | Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations |
| title_full_unstemmed | Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations |
| title_short | Fibromyalgia associated with repeated gadolinium contrast-enhanced MRI examinations |
| title_sort | fibromyalgia associated with repeated gadolinium contrast enhanced mri examinations |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320300431 |
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