Submicron-bubble-enhanced focused ultrasound for blood-brain barrier disruption and improved CNS drug delivery.

Submicron-bubble-enhanced focused ultrasound for blood-brain barrier disruption and improved CNS drug delivery.

The use of focused ultrasound (FUS) with microbubbles has been proven to induce transient blood-brain barrier opening (BBB-opening). However, FUS-induced inertial cavitation of microbubbles can also result in erythrocyte extravasations. Here we investigated whether induction of submicron bubbles to...

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Bibliographic Details
Main Authors: Ching-Hsiang Fan, Hao-Li Liu, Chien-Yu Ting, Ya-Hsuan Lee, Chih-Ying Huang, Yan-Jung Ma, Kuo-Chen Wei, Tzu-Chen Yen, Chih-Kuang Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096327&type=printable

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