Hyaluronan supports the limbal stem cell phenotype during ex vivo culture

Hyaluronan supports the limbal stem cell phenotype during ex vivo culture

Abstract Background Hyaluronan (HA) has previously been identified as an integral component of the limbal stem cell niche in vivo. In this study, we investigated whether a similar HA matrix is also expressed in vitro providing a niche supporting limbal epithelial stem cells (LESCs) during ex vivo ex...

Full description

Bibliographic Details
Main Authors: Sudan Puri, Isabel Y. Moreno, Mingxia Sun, Sudhir Verma, Xiao Lin, Tarsis F. Gesteira, Vivien J. Coulson-Thomas
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Stem Cell Research & Therapy
Subjects:
Limbal epithelial stem cells
Hyaluronan
Extracellular matrix
Limbal stem cell culture
Glycosaminoglycans
Online Access:https://doi.org/10.1186/s13287-022-03084-8

Internet

https://doi.org/10.1186/s13287-022-03084-8

Similar Items