Research on liquid biopsy for cancer: A bibliometric analysis

Background: In recent years, liquid biopsy has shown great potential for improving cancer diagnosis and treatment. This study aimed to explore the trends and prospects in liquid biopsy for cancer from a bibliometric perspective.Methods: Reviews and articles on liquid biopsy and cancer were collected...

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Main Authors: Shitao Jiang, Yaoge Liu, Yiyao Xu, Xinting Sang, Xin Lu
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402301352X
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author Shitao Jiang
Yaoge Liu
Yiyao Xu
Xinting Sang
Xin Lu
author_facet Shitao Jiang
Yaoge Liu
Yiyao Xu
Xinting Sang
Xin Lu
author_sort Shitao Jiang
collection DOAJ
description Background: In recent years, liquid biopsy has shown great potential for improving cancer diagnosis and treatment. This study aimed to explore the trends and prospects in liquid biopsy for cancer from a bibliometric perspective.Methods: Reviews and articles on liquid biopsy and cancer were collected from the Web of Science Core Collection (WoSCC). Key bibliometric characteristics were analyzed using CiteSpace. Co-occurrence analysis of keywords and co-citation analysis of references was performed.Results: A total of 6331 publications from 11 years of scientific research were retrieved. Ninety-five countries and 7004 institutions in liquid biopsy and cancer contributed. The United States (US) and China published the most articles. The institution with the most published articles was the University of Texas MD Anderson Cancer Center. The most published journals were Cancer and Frontiers in Oncology. “Bettegowda (2014)'' was the most cited reference with the highest burst strength in the last decade. Cluster analysis revealed that the recent hot topics were “circulating tumor cells,” “cancer,” and “exosomes.''Conclusions: This bibliometric analysis maps the basic knowledge structure of the field of liquid biopsy for cancer. The field is entering a phase of rapid development. The hot spots identified in this study deserve further investigation.
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spelling doaj.art-3f75f9feab804c9aae41ce4d4894f72d2023-04-05T08:20:59ZengElsevierHeliyon2405-84402023-03-0193e14145Research on liquid biopsy for cancer: A bibliometric analysisShitao Jiang0Yaoge Liu1Yiyao Xu2Xinting Sang3Xin Lu4Department of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaCorresponding author.; Department of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaBackground: In recent years, liquid biopsy has shown great potential for improving cancer diagnosis and treatment. This study aimed to explore the trends and prospects in liquid biopsy for cancer from a bibliometric perspective.Methods: Reviews and articles on liquid biopsy and cancer were collected from the Web of Science Core Collection (WoSCC). Key bibliometric characteristics were analyzed using CiteSpace. Co-occurrence analysis of keywords and co-citation analysis of references was performed.Results: A total of 6331 publications from 11 years of scientific research were retrieved. Ninety-five countries and 7004 institutions in liquid biopsy and cancer contributed. The United States (US) and China published the most articles. The institution with the most published articles was the University of Texas MD Anderson Cancer Center. The most published journals were Cancer and Frontiers in Oncology. “Bettegowda (2014)'' was the most cited reference with the highest burst strength in the last decade. Cluster analysis revealed that the recent hot topics were “circulating tumor cells,” “cancer,” and “exosomes.''Conclusions: This bibliometric analysis maps the basic knowledge structure of the field of liquid biopsy for cancer. The field is entering a phase of rapid development. The hot spots identified in this study deserve further investigation.http://www.sciencedirect.com/science/article/pii/S240584402301352XCancerLiquid biopsyBibliometric analysisCiteSpaceFrontiers
spellingShingle Shitao Jiang
Yaoge Liu
Yiyao Xu
Xinting Sang
Xin Lu
Research on liquid biopsy for cancer: A bibliometric analysis
Heliyon
Cancer
Liquid biopsy
Bibliometric analysis
CiteSpace
Frontiers
title Research on liquid biopsy for cancer: A bibliometric analysis
title_full Research on liquid biopsy for cancer: A bibliometric analysis
title_fullStr Research on liquid biopsy for cancer: A bibliometric analysis
title_full_unstemmed Research on liquid biopsy for cancer: A bibliometric analysis
title_short Research on liquid biopsy for cancer: A bibliometric analysis
title_sort research on liquid biopsy for cancer a bibliometric analysis
topic Cancer
Liquid biopsy
Bibliometric analysis
CiteSpace
Frontiers
url http://www.sciencedirect.com/science/article/pii/S240584402301352X
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