Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells.

Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells.

Drosophila female germline stem cells (GSCs) reside adjacent to a cellular niche that secretes Bone Morphogenetic Protein (BMP) ligands and anchors the GSCs through adherens junctions. The GSCs divide asymmetrically such that one daughter remains in the niche as a GSC, while the other is born away f...

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Bibliographic Details
Main Authors:	Wen Lu, M Olivia Casanueva, Anthony P Mahowald, Mihoko Kato, David Lauterbach, Edwin L Ferguson
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS Biology
Online Access:	http://europepmc.org/articles/PMC3389017?pdf=render

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