Astrovirus Diagnostics
Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent o...
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Format: | Article |
Language: | English |
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MDPI AG
2017-01-01
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Series: | Viruses |
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Online Access: | http://www.mdpi.com/1999-4915/9/1/10 |
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author | Philippe Pérot Marc Lecuit Marc Eloit |
author_facet | Philippe Pérot Marc Lecuit Marc Eloit |
author_sort | Philippe Pérot |
collection | DOAJ |
description | Various methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised individuals in association with central nervous system (CNS) infections. This work reviews the past and current methods for astrovirus detection and their uses in both research laboratories and for medical diagnostic purposes. |
first_indexed | 2024-04-14T01:31:49Z |
format | Article |
id | doaj.art-3f76f15d552944faad805917e7252be6 |
institution | Directory Open Access Journal |
issn | 1999-4915 |
language | English |
last_indexed | 2024-04-14T01:31:49Z |
publishDate | 2017-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Viruses |
spelling | doaj.art-3f76f15d552944faad805917e7252be62022-12-22T02:20:08ZengMDPI AGViruses1999-49152017-01-01911010.3390/v9010010v9010010Astrovirus DiagnosticsPhilippe Pérot0Marc Lecuit1Marc Eloit2Institut Pasteur, Biology of Infection Unit, Inserm U1117, Laboratory of Pathogen Discovery, 75015 Paris, FranceInstitut Pasteur, Biology of Infection Unit, Inserm U1117, Laboratory of Pathogen Discovery, 75015 Paris, FranceInstitut Pasteur, Biology of Infection Unit, Inserm U1117, Laboratory of Pathogen Discovery, 75015 Paris, FranceVarious methods exist to detect an astrovirus infection. Current methods include electron microscopy (EM), cell culture, immunoassays, polymerase chain reaction (PCR) and various other molecular approaches that can be applied in the context of diagnostic or in surveillance studies. With the advent of metagenomics, novel human astrovirus (HAstV) strains have been found in immunocompromised individuals in association with central nervous system (CNS) infections. This work reviews the past and current methods for astrovirus detection and their uses in both research laboratories and for medical diagnostic purposes.http://www.mdpi.com/1999-4915/9/1/10astrovirusvirologydetection methodsmolecular diagnostics |
spellingShingle | Philippe Pérot Marc Lecuit Marc Eloit Astrovirus Diagnostics Viruses astrovirus virology detection methods molecular diagnostics |
title | Astrovirus Diagnostics |
title_full | Astrovirus Diagnostics |
title_fullStr | Astrovirus Diagnostics |
title_full_unstemmed | Astrovirus Diagnostics |
title_short | Astrovirus Diagnostics |
title_sort | astrovirus diagnostics |
topic | astrovirus virology detection methods molecular diagnostics |
url | http://www.mdpi.com/1999-4915/9/1/10 |
work_keys_str_mv | AT philippeperot astrovirusdiagnostics AT marclecuit astrovirusdiagnostics AT marceloit astrovirusdiagnostics |