CORRECTION OF INTERFERON-α-INDUCED DENDRITIC CELL DYSFUNCTIONS IN IMMUNOCOMPROMISED PATIENTS

CORRECTION OF INTERFERON-α-INDUCED DENDRITIC CELL DYSFUNCTIONS IN IMMUNOCOMPROMISED PATIENTS

The correction of impaired functions of in vitro generated interferon-alpha-induced dendritic cells (IFN-DCs) in patients with malignant brain tumors (n = 8), malignant lymphomas (n = 14) and pulmonary tuberculosis (n = 26) was analyzed in the present study. The principal possibility of restoring re...

Full description

Bibliographic Details
Main Authors:	O. Yu. Leplina, L. V. Sakhno, A. A. Ostanin, S. S. Bogachev, E. R. Chernykh
Format:	Article
Language:	Russian
Published:	Scientific Сentre for Family Health and Human Reproduction Problems 2012-05-01
Series:	Acta Biomedica Scientifica
Subjects:	dendritic cells interferon-alpha correction cytotoxicity allostimulatory activity
Online Access:	https://www.actabiomedica.ru/jour/article/view/896

Similar Items

FUNCTIONAL ACTIVITY OF IFNα- AND IL-4-INDUCED HUMAN DENDRITIC CELLS: A COMPARATIVE STUDY
by: O. Yu. Leplina, et al.
Published: (2014-07-01)

EFFECT OF DEXAMETHASONE ON INTERFERON-α-INDUCED DIFFERENTIATION OF MONOCYTES TO DENDRITIC CELLS
by: Yu. D. Kurochkina, et al.
Published: (2016-08-01)

Relationship between the functional activity of <i>in vitro</i> generated monocyte-derived dendritic cells and the presence of CD16 <sup>+</sup> cells among peripheral blood monocytes
by: T. V. Tyrinova, et al.
Published: (2020-04-01)

ROLE OF TNFα/TNF-R1-SIGNALING PATHWAY IN CYTOTOXIC ACTIVITY OF DENDRITIC CELLS AGAINST GLIOBLASTOMA CELL LINES
by: T. V. Tyrinova, et al.
Published: (2018-06-01)

INVOLVEMENT OF PERFORIN/GRANZYME B-DEPENDENT SIGNALING PATHWAY IN CYTOTOXIC ACTIVITY OF DENDRITIC CELLS TOWARDS HUMAN GLIOBLASTOMA CELLS
by: T. V. Tyrinova, et al.
Published: (2017-08-01)

IFNα-INDUCED DENDRITIC CELLS IN PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR SENSITIVITY TO DEXAMETHASONE
by: E. R. Chernykh, et al.
Published: (2017-07-01)

Defective Regulation of Membrane TNFα Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells
by: Tamara Tyrinova, et al.
Published: (2020-04-01)

POSSIBILITIES OF REPLACEMENT INTERFERON THERAPY TO TREAT ATOPIC DERMATITIS IN IMMUNOCOMPROMISED PATIENTS
by: L. P. Sizyakina, et al.
Published: (2017-07-01)

Effect of Intranodally Administered Dendritic Cell-Based HIV Vaccine in Combination With Pegylated Interferon α-2a on Viral Control Following ART Discontinuation: A Phase 2A Randomized Clinical Trial
by: Lorna Leal, et al.
Published: (2021-11-01)

Induction of HCV-specific cell response in vitro by dendritic cells generated with interferon-α
by: E. R. Chernykh, et al.
Published: (2019-05-01)

Type I interferons as stimulators of DC-mediated cross-priming: impact on anti-tumor response
by: Giovanna eSchiavoni, et al.
Published: (2013-12-01)

INFLUENCE OF DEXAMETHASONE-MODIFIED DENDRITIC CELLS GENERATED WITH IFNα UPON AUTOLOGOUS T LYMPHOCYTE FUNCTIONS IN THE PATIENTS WITH RHEUMATOID ARTHRITIS
by: Yu. D. Kurochkina, et al.
Published: (2019-12-01)

ANTI-TUMOR ACTIVITY OF DENDRITIC CELLS IN HEALTHY DONORS AND PATIENTS WITH BRAIN TUMORS
by: E. R. Chernykh, et al.
Published: (2014-07-01)

Phenotypical Diversification of Early IFNα-Producing Human Plasmacytoid Dendritic Cells Using Droplet-Based Microfluidics
by: Laura C. Van Eyndhoven, et al.
Published: (2021-04-01)

SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights
by: Qiao Zhou, et al.
Published: (2021-04-01)

Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue
by: Vinit Upasani, et al.
Published: (2020-12-01)

FUNCTIONAL PROPERTIES OF IFNΑ-INDUCED DENDRITIC CELLS IN THE PATIENTS WITH PULMONARY TUBERCULOSIS
by: L. V. Sakhno, et al.
Published: (2014-07-01)

Interferon alpha (IFN-α) in systemic lupus erythematosus (SLE)
by: Sara Moqbil, et al.
Published: (2022-11-01)

Deciphering the role of interferon alpha signaling and microenvironment crosstalk in inflammatory breast cancer
by: Olivia K. Provance, et al.
Published: (2019-05-01)

Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses
by: Brian Webster, et al.
Published: (2018-06-01)

Shared and Unique Features of Human Interferon-Beta and Interferon-Alpha Subtypes
by: Megen C. Wittling, et al.
Published: (2021-01-01)

Treatment with Ad5-Porcine Interferon-α Attenuates Ebolavirus Disease in Pigs
by: Chandrika Senthilkumaran, et al.
Published: (2022-04-01)

INTERLEUKIN-10 REGULATES PD-1-B7-H1-MEDIATED CYTOTOXIC ACTIVITY OF DENDRITIC CELLS
by: L. V. Sakhno, et al.
Published: (2012-05-01)

Regulatory NLRs Control the RLR-Mediated Type I Interferon and Inflammatory Responses in Human Dendritic Cells
by: Tünde Fekete, et al.
Published: (2018-10-01)

Sources of Type I Interferons in Infectious Immunity: Plasmacytoid Dendritic Cells Not Always in the Driver's Seat
by: Shafaqat Ali, et al.
Published: (2019-04-01)

CHARACTERISTICS OF SIGNALING PATHWAYS MEDIATING A CYTOTOXIC EFFECT OF DENDRITIC CELLS UPON ACTIVATED Т LYMPHOCYTES AND NK CELLS
by: T. V. Tyrinova, et al.
Published: (2014-07-01)

Flaxseed Prevents Interferon-alpha Induced Depressive Behavior in Mice: the α-Linolenic Acid is Essential
by: Azadeh Mesripour*, et al.
Published: (2021-01-01)

Interferon-λs and Plasmacytoid Dendritic Cells: A Close Relationship
by: Giulia Finotti, et al.
Published: (2017-08-01)

Significance of the interferon (IFN) in the therapy
by: Sabina Mahmutović, et al.
Published: (2004-11-01)

TYROSINE KINASE INHIBITORS AND INTERFERON
by: Maria Dimou, et al.
Published: (2014-01-01)

Insights Into Type I and III Interferons in Asthma and Exacerbations
by: Helen E. Rich, et al.
Published: (2020-09-01)

Phenotypic and functional profile of IFN-α-differentiated dendritic cells (IFN-DCs) from HIV-infected individuals
by: Bruna Tereso Santillo, et al.
Published: (2019-09-01)

Type I Interferon Production of Plasmacytoid Dendritic Cells under Control
by: Dóra Bencze, et al.
Published: (2021-04-01)

Interferon alpha and non-specific markers of inflammation in patients with systemic lupus erythematosus
by: Lamija Zečević, et al.
Published: (2022-08-01)

Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia
by: Murtuza Nuruddin, et al.
Published: (2022-01-01)

Phosphate-modified CpG oligonucleotides induce in vitro maturation of human myeloid dendritic cells
by: A. A. Ostanin, et al.
Published: (2020-10-01)

IFN-Alpha-Mediated Differentiation of Dendritic Cells for Cancer Immunotherapy: Advances and Perspectives
by: Caterina Lapenta, et al.
Published: (2020-10-01)

Efficiency of Interferon-γ in Activating Dendritic Cells and Its Potential Synergy with Toll-like Receptor Agonists
by: Yuanzhi Bian, et al.
Published: (2023-05-01)

Autoanticuerpos en pacientes hematológicos tratados con interferón alfa
by: Antonio A Bencomo Hernández, et al.

A stepping stone in treating dendritic keratitis
by: Hosam Sheha, MD, PhD, et al.
Published: (2017-09-01)