A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells
Background: Early diagnosis and treatment are key to improving survival and prognosis of patients with lung cancer. Liquid biopsy and artificial intelligence (AI) can help diagnose early lung cancer. Case presentation: We present a 68-year-old female with a family history of pulmonary nodules withou...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2022-12-01
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| Series: | Clinical eHealth |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2588914122000235 |
| _version_ | 1811177005053378560 |
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| author | Lu Wang Dawei Yang Lin Tong Yuanlin Song Chunxue Bai |
| author_facet | Lu Wang Dawei Yang Lin Tong Yuanlin Song Chunxue Bai |
| author_sort | Lu Wang |
| collection | DOAJ |
| description | Background: Early diagnosis and treatment are key to improving survival and prognosis of patients with lung cancer. Liquid biopsy and artificial intelligence (AI) can help diagnose early lung cancer. Case presentation: We present a 68-year-old female with a family history of pulmonary nodules without smoking history who found multiple nodules in the lungs on physical examination. Malignant lung nodules were diagnosed based on AI evaluation and 341 circulating abnormal cells (CACs). Surgical resection confirmed the diagnosis of pulmonary adenocarcinoma and the CACs decreased to 151 at postoperative follow-up in one month and to 54 six months after surgery. Conclusion: CACs helps to improve the accuracy of AI diagnosis of early lung cancer and the prognosis of patients with lung cancer at follow-up. |
| first_indexed | 2024-04-10T20:02:20Z |
| format | Article |
| id | doaj.art-3f7b62566f7e4053b7b8c5918591d479 |
| institution | Directory Open Access Journal |
| issn | 2588-9141 |
| language | English |
| last_indexed | 2024-04-10T20:02:20Z |
| publishDate | 2022-12-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Clinical eHealth |
| spelling | doaj.art-3f7b62566f7e4053b7b8c5918591d4792023-01-27T04:20:38ZengKeAi Communications Co., Ltd.Clinical eHealth2588-91412022-12-015106108A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cellsLu Wang0Dawei Yang1Lin Tong2Yuanlin Song3Chunxue Bai4Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China; Shanghai Engineering Research Center of Internet of Things for Respiratory Medicine, Shanghai, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, ChinaDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China; Shanghai Engineering Research Center of Internet of Things for Respiratory Medicine, Shanghai, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China; Zhongshan Hospital (Xiamen), Fudan University, Xiamen, ChinaDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China; Shanghai Engineering Research Center of Internet of Things for Respiratory Medicine, Shanghai, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China; Zhongshan Hospital (Xiamen), Fudan University, Xiamen, ChinaDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China; Shanghai Engineering Research Center of Internet of Things for Respiratory Medicine, Shanghai, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China; Shanghai Institute of Infectious Disease and Biosecurity, Shanghai, China; Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China; Corresponding authors at: Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China.Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China; Shanghai Engineering Research Center of Internet of Things for Respiratory Medicine, Shanghai, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Shanghai, China; Shanghai Institute of Infectious Disease and Biosecurity, Shanghai, China; Corresponding authors at: Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital Fudan University, Shanghai, China.Background: Early diagnosis and treatment are key to improving survival and prognosis of patients with lung cancer. Liquid biopsy and artificial intelligence (AI) can help diagnose early lung cancer. Case presentation: We present a 68-year-old female with a family history of pulmonary nodules without smoking history who found multiple nodules in the lungs on physical examination. Malignant lung nodules were diagnosed based on AI evaluation and 341 circulating abnormal cells (CACs). Surgical resection confirmed the diagnosis of pulmonary adenocarcinoma and the CACs decreased to 151 at postoperative follow-up in one month and to 54 six months after surgery. Conclusion: CACs helps to improve the accuracy of AI diagnosis of early lung cancer and the prognosis of patients with lung cancer at follow-up.http://www.sciencedirect.com/science/article/pii/S2588914122000235Circulating abnormal cells (CACs)Artificial intelligence (AI)Lung cancer |
| spellingShingle | Lu Wang Dawei Yang Lin Tong Yuanlin Song Chunxue Bai A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells Clinical eHealth Circulating abnormal cells (CACs) Artificial intelligence (AI) Lung cancer |
| title | A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells |
| title_full | A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells |
| title_fullStr | A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells |
| title_full_unstemmed | A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells |
| title_short | A 68-year-old female with pulmonary nodules harboring 341 circulating abnormal cells |
| title_sort | 68 year old female with pulmonary nodules harboring 341 circulating abnormal cells |
| topic | Circulating abnormal cells (CACs) Artificial intelligence (AI) Lung cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2588914122000235 |
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