Mediating Effect of Diabetes Mellitus on the Association Between Chromosome 9p21.3 Locus and Myocardial Infarction Risk: A Case-Control Study in Shanghai, China

Mediating Effect of Diabetes Mellitus on the Association Between Chromosome 9p21.3 Locus and Myocardial Infarction Risk: A Case-Control Study in Shanghai, China

Background: Previous genome-wide association studies revealed that the chromosome 9p21.3 locus is associated with an increased risk of myocardial infarction (MI) and diabetes mellitus (DM). However, it is unclear whether the 9p21.3-MI association is direct or mediated by pathways related to DM.Study...

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Bibliografiske detaljer
Main Authors:	Zhijun Wu, Haihui Sheng, Xiuxiu Su, Xiang Gao, Lin Lu, Wei Jin
Format:	Article
Sprog:	English
Udgivet:	Frontiers Media S.A. 2018-07-01
Serier:	Frontiers in Endocrinology
Fag:	mediation analysis myocardial infarction diabetes mellitus genetic risk score metabolic disease
Online adgang:	https://www.frontiersin.org/article/10.3389/fendo.2018.00362/full

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