QuEChERS-ultra performance liquid chromatography-tandem mass spectrometry for the determination of erythromycin in fishy products(QuEChERS-超高效液相色谱串联质谱法测定水产品中红霉素残留)

QuEChERS-ultra performance liquid chromatography-tandem mass spectrometry for the determination of erythromycin in fishy products(QuEChERS-超高效液相色谱串联质谱法测定水产品中红霉素残留)

建立了超高效液相色谱串联质谱法测定水产品中的红霉素残留量.样品用改进的QuEChERS（快速、简单、廉价、高效、灵活和安全）进行提取净化，经乙腈快速提取，无水硫酸镁和氯化钠除水后，用N-丙基乙二胺(PSA)净化，液相色谱串联质谱分析测定.在ACQUITY UPLC BEH C18色谱柱上进行分离，采用梯度洗脱，以0.1%甲酸水溶液和甲醇为流动相，电喷雾正离子电离，多反应监测模式，内标法定量.结果表明：红霉素浓度在0.5~50 µg • L-1时具有良好的线性关系，相关系数为0.997 6，定量限为0.3 µg • kg-1，回收率为87.6%~96.1%，相对标准偏差为2.2%~5.3%.本方...

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Bibliographic Details
Main Authors: YANZhongyong(严忠雍), ZHANGXiaojun(张小军), LIPeipei(李佩佩), FANGYi(方益), YULiang(喻亮), ZHANGShuai(张帅), ZHUYin(祝银), LIQiang(李强)
Format: Article
Language:zho
Published: Zhejiang University Press 2017-05-01
Series:Zhejiang Daxue xuebao. Lixue ban
Subjects:
quechers
液相色谱串联质谱
水产品
红霉素
Online Access:https://doi.org/10.3785/j.issn.1008-9497.2017.03.015

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