Is there a causal association between gestational diabetes mellitus and immune mediators? A bidirectional Mendelian randomization analysis

Is there a causal association between gestational diabetes mellitus and immune mediators? A bidirectional Mendelian randomization analysis

BackgroundDiabetes that only appears or is diagnosed during pregnancy is referred to as gestational diabetes mellitus (GDM). The maternal physiological immune profile is essential for a positive pregnancy outcome. However, the causal relationship between GDM and immunophenotypes is not fully defined...

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Bibliographic Details
Main Authors: Zhangxin Ji, Chenxu Zhang, Jingjing Yuan, Qing He, Xinyu Zhang, Dongmei Yang, Na Xu, Jun Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Endocrinology
Subjects:
gestational diabetes mellitus
immunity
causal inference
genetic variation
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1358144/full

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