PET imaging of microglia using PBR28suv determines therapeutic efficacy of autologous bone marrow mononuclear cells therapy in traumatic brain injury
Abstract Traumatic brain injury (TBI) results in activated microglia. Activated microglia can be measured in vivo by using positron emission topography (PET) ligand peripheral benzodiazepine receptor standardized uptake values (PBR28suv). Cell based therapies have utilized autologous bone marrow mon...
Main Authors: | Supinder S. Bedi, Michael C. Scott, Max A. Skibber, Akshita Kumar, Henry W. Caplan, Hasen Xue, David Sequeira, Alison L. Speer, Fanni Cardenas, Franciska Gudenkauf, Karen Uray, Amit K. Srivastava, Alan R. Prossin, Charles S. Cox |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-43245-0 |
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