The future excess fraction model for calculating burden of disease

Abstract Background Estimates of the burden of disease caused by a particular agent are used to assist in making policy and prioritizing actions. Most estimations have employed the attributable fraction approach, which estimates the proportion of disease cases or deaths in a specific year which are...

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Main Authors: Lin Fritschi, Jayzii Chan, Sally J. Hutchings, Tim R. Driscoll, Adrian Y. W. Wong, Renee N. Carey
Format: Article
Language:English
Published: BMC 2016-05-01
Series:BMC Public Health
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12889-016-3066-1
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author Lin Fritschi
Jayzii Chan
Sally J. Hutchings
Tim R. Driscoll
Adrian Y. W. Wong
Renee N. Carey
author_facet Lin Fritschi
Jayzii Chan
Sally J. Hutchings
Tim R. Driscoll
Adrian Y. W. Wong
Renee N. Carey
author_sort Lin Fritschi
collection DOAJ
description Abstract Background Estimates of the burden of disease caused by a particular agent are used to assist in making policy and prioritizing actions. Most estimations have employed the attributable fraction approach, which estimates the proportion of disease cases or deaths in a specific year which are attributable to past exposure to a particular agent. While this approach has proven extremely useful in quantifying health effects, it requires historical data on exposures which are not always available. Methods We present an alternative method, the future excess fraction method, which is based on the lifetime risk approach, and which requires current rather than historical exposure data. This method estimates the future number of exposure-related disease cases or deaths occurring in the subgroup of the population who were exposed to the particular agent in a specific year. We explain this method and use publically-available data on current asbestos exposure and mesothelioma incidence to demonstrate the use of the method. Conclusions Our approach to modelling burden of disease is useful when there are no historical measures of exposure and where future disease rates can be projected on person years at risk.
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spelling doaj.art-3f8eba563b3449c9821da394e9c911572022-12-22T03:18:57ZengBMCBMC Public Health1471-24582016-05-011611810.1186/s12889-016-3066-1The future excess fraction model for calculating burden of diseaseLin Fritschi0Jayzii Chan1Sally J. Hutchings2Tim R. Driscoll3Adrian Y. W. Wong4Renee N. Carey5School of Public Health, Curtin UniversityDepartment of Mathematics and Statistics, Curtin UniversityDepartment of Epidemiology and Biostatistics, Imperial College LondonSchool of Public Health, University of SydneyDepartment of Mathematics and Statistics, Curtin UniversitySchool of Public Health, Curtin UniversityAbstract Background Estimates of the burden of disease caused by a particular agent are used to assist in making policy and prioritizing actions. Most estimations have employed the attributable fraction approach, which estimates the proportion of disease cases or deaths in a specific year which are attributable to past exposure to a particular agent. While this approach has proven extremely useful in quantifying health effects, it requires historical data on exposures which are not always available. Methods We present an alternative method, the future excess fraction method, which is based on the lifetime risk approach, and which requires current rather than historical exposure data. This method estimates the future number of exposure-related disease cases or deaths occurring in the subgroup of the population who were exposed to the particular agent in a specific year. We explain this method and use publically-available data on current asbestos exposure and mesothelioma incidence to demonstrate the use of the method. Conclusions Our approach to modelling burden of disease is useful when there are no historical measures of exposure and where future disease rates can be projected on person years at risk.http://link.springer.com/article/10.1186/s12889-016-3066-1Burden of diseaseMethodologyPolicyPrevention
spellingShingle Lin Fritschi
Jayzii Chan
Sally J. Hutchings
Tim R. Driscoll
Adrian Y. W. Wong
Renee N. Carey
The future excess fraction model for calculating burden of disease
BMC Public Health
Burden of disease
Methodology
Policy
Prevention
title The future excess fraction model for calculating burden of disease
title_full The future excess fraction model for calculating burden of disease
title_fullStr The future excess fraction model for calculating burden of disease
title_full_unstemmed The future excess fraction model for calculating burden of disease
title_short The future excess fraction model for calculating burden of disease
title_sort future excess fraction model for calculating burden of disease
topic Burden of disease
Methodology
Policy
Prevention
url http://link.springer.com/article/10.1186/s12889-016-3066-1
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