Transcriptomic analysis of spleen B cell revealed the molecular basis of bursopentin on B cell differentiation

Transcriptomic analysis of spleen B cell revealed the molecular basis of bursopentin on B cell differentiation

Abstract The bursa of Fabricius, the acknowledged humoral immune organ unique to birds, plays a vital role in B cell development. Bursopentin (BP5) derived from the bursa is reported to induce the development and formation of B cells. However, the mechanism of BP5 on B cell differentiation is still...

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Bibliographic Details
Main Authors: Ze Zhang, Jiaxi Cai, Shanshan Hao, Chenfei Li, Jiajing Chen, Tongtong Li, Xiuli Feng
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Veterinary Research
Subjects:
BP5
B cell differentiation
enrichment pathways
transcriptional factor
immune induction
Online Access:https://doi.org/10.1186/s13567-022-01123-z

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