A concerted ATPase cycle of the protein transporter AAA-ATPase Bcs1

Abstract Bcs1, a homo-heptameric transmembrane AAA-ATPase, facilitates folded Rieske iron-sulfur protein translocation across the inner mitochondrial membrane. Structures in different nucleotide states (ATPγS, ADP, apo) provided conformational snapshots, but the kinetics and structural transitions o...

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Bibliographic Details
Main Authors: Yangang Pan, Jingyu Zhan, Yining Jiang, Di Xia, Simon Scheuring
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41806-5

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