A concerted ATPase cycle of the protein transporter AAA-ATPase Bcs1
Abstract Bcs1, a homo-heptameric transmembrane AAA-ATPase, facilitates folded Rieske iron-sulfur protein translocation across the inner mitochondrial membrane. Structures in different nucleotide states (ATPγS, ADP, apo) provided conformational snapshots, but the kinetics and structural transitions o...
Main Authors: | Yangang Pan, Jingyu Zhan, Yining Jiang, Di Xia, Simon Scheuring |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41806-5 |
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