Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine

Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine

Plasmodium vivax is a malaria-causing pathogen that establishes a dormant form in the liver (the hypnozoite), which can activate weeks, months, or years after the primary infection to cause a relapse, characterized by secondary blood-stage infection. These asymptomatic and undetectable latent liver...

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Bibliografische gegevens
Hoofdauteurs: Erika L. Flannery, Niwat Kangwanrangsan, Vorada Chuenchob, Wanlapa Roobsoong, Matthew Fishbaugher, Kevin Zhou, Zachary P. Billman, Thomas Martinson, Tayla M. Olsen, Carola Schäfer, Brice Campo, Sean C. Murphy, Sebastian A. Mikolajczak, Stefan H.I. Kappe, Jetsumon Sattabongkot
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2022-09-01
Reeks:Molecular Therapy: Methods & Clinical Development
Onderwerpen:
Plasmodium vivax
malaria
latency
hypnozoite
primaquine
liver-chimeric humanized mice
Online toegang:http://www.sciencedirect.com/science/article/pii/S2329050122001085

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http://www.sciencedirect.com/science/article/pii/S2329050122001085

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