Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

Implantable biomaterials evoke foreign body responses in the central nervous system. The authors compare hydrogel-based biomaterials to identify cellular interactions and molecular mechanisms that drive different types of foreign body responses that have different effects on biomaterial function.

Bibliographic Details
Main Authors: Timothy M. OʼShea, Alexander L. Wollenberg, Jae H. Kim, Yan Ao, Timothy J. Deming, Michael V. Sofroniew
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19906-3

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