Mesenchymal Stem Cell Senescence and Osteogenesis

Mesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvena...

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Main Authors: Artaria Tjempakasari, Heri Suroto, Djoko Santoso
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/1/61
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author Artaria Tjempakasari
Heri Suroto
Djoko Santoso
author_facet Artaria Tjempakasari
Heri Suroto
Djoko Santoso
author_sort Artaria Tjempakasari
collection DOAJ
description Mesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvenation medicine. MSCs are also beneficial in recipient tissue and differentiate as a breakthrough strategy through paracrine activity. Many databases have shown MSC-based treatment can be beneficial in the reduction of osteogenesis induced by senescence. In this article, we will discuss the potential effect of MSCs in senescence cells related to osteogenesis.
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spelling doaj.art-3f9e65d1d7c24869bf97878557237eea2023-11-23T14:36:17ZengMDPI AGMedicina1010-660X1648-91442021-12-015816110.3390/medicina58010061Mesenchymal Stem Cell Senescence and OsteogenesisArtaria Tjempakasari0Heri Suroto1Djoko Santoso2Department of Internal Medicine, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaDepartment of Orthopedic & Traumatology, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaMesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvenation medicine. MSCs are also beneficial in recipient tissue and differentiate as a breakthrough strategy through paracrine activity. Many databases have shown MSC-based treatment can be beneficial in the reduction of osteogenesis induced by senescence. In this article, we will discuss the potential effect of MSCs in senescence cells related to osteogenesis.https://www.mdpi.com/1648-9144/58/1/61cellular senescencemesenchymal stem cellsMSCs senescenceosteogenesis
spellingShingle Artaria Tjempakasari
Heri Suroto
Djoko Santoso
Mesenchymal Stem Cell Senescence and Osteogenesis
Medicina
cellular senescence
mesenchymal stem cells
MSCs senescence
osteogenesis
title Mesenchymal Stem Cell Senescence and Osteogenesis
title_full Mesenchymal Stem Cell Senescence and Osteogenesis
title_fullStr Mesenchymal Stem Cell Senescence and Osteogenesis
title_full_unstemmed Mesenchymal Stem Cell Senescence and Osteogenesis
title_short Mesenchymal Stem Cell Senescence and Osteogenesis
title_sort mesenchymal stem cell senescence and osteogenesis
topic cellular senescence
mesenchymal stem cells
MSCs senescence
osteogenesis
url https://www.mdpi.com/1648-9144/58/1/61
work_keys_str_mv AT artariatjempakasari mesenchymalstemcellsenescenceandosteogenesis
AT herisuroto mesenchymalstemcellsenescenceandosteogenesis
AT djokosantoso mesenchymalstemcellsenescenceandosteogenesis