Mesenchymal Stem Cell Senescence and Osteogenesis
Mesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvena...
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Format: | Article |
Language: | English |
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MDPI AG
2021-12-01
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Series: | Medicina |
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Online Access: | https://www.mdpi.com/1648-9144/58/1/61 |
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author | Artaria Tjempakasari Heri Suroto Djoko Santoso |
author_facet | Artaria Tjempakasari Heri Suroto Djoko Santoso |
author_sort | Artaria Tjempakasari |
collection | DOAJ |
description | Mesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvenation medicine. MSCs are also beneficial in recipient tissue and differentiate as a breakthrough strategy through paracrine activity. Many databases have shown MSC-based treatment can be beneficial in the reduction of osteogenesis induced by senescence. In this article, we will discuss the potential effect of MSCs in senescence cells related to osteogenesis. |
first_indexed | 2024-03-10T01:00:29Z |
format | Article |
id | doaj.art-3f9e65d1d7c24869bf97878557237eea |
institution | Directory Open Access Journal |
issn | 1010-660X 1648-9144 |
language | English |
last_indexed | 2024-03-10T01:00:29Z |
publishDate | 2021-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Medicina |
spelling | doaj.art-3f9e65d1d7c24869bf97878557237eea2023-11-23T14:36:17ZengMDPI AGMedicina1010-660X1648-91442021-12-015816110.3390/medicina58010061Mesenchymal Stem Cell Senescence and OsteogenesisArtaria Tjempakasari0Heri Suroto1Djoko Santoso2Department of Internal Medicine, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaDepartment of Orthopedic & Traumatology, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Airlangga University, Dr. Soetomo Teaching Hospital, Surabaya 60286, IndonesiaMesenchymal stem cells (MSCs) are stem cells with the potential ability to differentiate into various cells and the ability to self-renew and resemble fibroblasts. These cells can adhere to plastic to facilitate the culture process. MSCs can be used in research into tissue biotechnology and rejuvenation medicine. MSCs are also beneficial in recipient tissue and differentiate as a breakthrough strategy through paracrine activity. Many databases have shown MSC-based treatment can be beneficial in the reduction of osteogenesis induced by senescence. In this article, we will discuss the potential effect of MSCs in senescence cells related to osteogenesis.https://www.mdpi.com/1648-9144/58/1/61cellular senescencemesenchymal stem cellsMSCs senescenceosteogenesis |
spellingShingle | Artaria Tjempakasari Heri Suroto Djoko Santoso Mesenchymal Stem Cell Senescence and Osteogenesis Medicina cellular senescence mesenchymal stem cells MSCs senescence osteogenesis |
title | Mesenchymal Stem Cell Senescence and Osteogenesis |
title_full | Mesenchymal Stem Cell Senescence and Osteogenesis |
title_fullStr | Mesenchymal Stem Cell Senescence and Osteogenesis |
title_full_unstemmed | Mesenchymal Stem Cell Senescence and Osteogenesis |
title_short | Mesenchymal Stem Cell Senescence and Osteogenesis |
title_sort | mesenchymal stem cell senescence and osteogenesis |
topic | cellular senescence mesenchymal stem cells MSCs senescence osteogenesis |
url | https://www.mdpi.com/1648-9144/58/1/61 |
work_keys_str_mv | AT artariatjempakasari mesenchymalstemcellsenescenceandosteogenesis AT herisuroto mesenchymalstemcellsenescenceandosteogenesis AT djokosantoso mesenchymalstemcellsenescenceandosteogenesis |