Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants?
CONTEXT: Adequacy of glucose infusion may be monitored via the glycosuria levels, as there is a relationship between glycemia and glycosuria regulated by the renal glucose threshold. In the neonatal period, however, this relationship is not so clear. OBJECTIVE: To evaluate the occurrence of glycosur...
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
1999-01-01
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| Series: | São Paulo Medical Journal |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000100004&lng=en&tlng=en |
| _version_ | 1811327299065217024 |
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| author | Mário Cícero Falcão Cléa Rodrigues Leone José Lauro Araújo Ramos |
| author_facet | Mário Cícero Falcão Cléa Rodrigues Leone José Lauro Araújo Ramos |
| author_sort | Mário Cícero Falcão |
| collection | DOAJ |
| description | CONTEXT: Adequacy of glucose infusion may be monitored via the glycosuria levels, as there is a relationship between glycemia and glycosuria regulated by the renal glucose threshold. In the neonatal period, however, this relationship is not so clear. OBJECTIVE: To evaluate the occurrence of glycosuria in preterm infants submitted to glucose infusion and to verify the relationship between glycosuria and blood glucose level. DESIGN: Accuracy study. SETTING: Neonatal intensive care unit of General Maternity Hospital. PATIENTS: 40 preterm newborns receiving glucose infusion. PROCEDURES: 511 concomitant determinations of glycemia and glycosuria were performed. These 511 pairs were divided into stable and unstable, according to the clinical status of the newborn at the time of data collection, and they were studied in relation to the gestational age, birth weight and glucose infusion rate. RESULTS: The results revealed a greater frequency of glycosuria in gestational age <FONT FACE="Symbol">£</font> 30 weeks, birth weight <1500 g and glucose infusion rate > 6 mg/kg/min. Eight (25.8%) episodes of positive glycosuria occurred in the absence of hyperglycemia, indicating only a moderate concordance between them. CONCLUSION: Glycosuria alone is an unreliable marker of blood glucose concentration and adequacy of glucose infusion rate. It is therefore necessary to monitor blood glucose levels in infants submitted to continuous glucose infusion. |
| first_indexed | 2024-04-13T15:04:12Z |
| format | Article |
| id | doaj.art-3f9f3fe5796346d0a316fa4bd215786d |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-04-13T15:04:12Z |
| publishDate | 1999-01-01 |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-3f9f3fe5796346d0a316fa4bd215786d2022-12-22T02:42:12ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94601999-01-011171192410.1590/S1516-31801999000100004S1516-31801999000100004Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants?Mário Cícero Falcão0Cléa Rodrigues Leone1José Lauro Araújo Ramos2Santa Catarina Hospital (São Paulo) NurserySanta Catarina Hospital (São Paulo) NurserySanta Catarina Hospital (São Paulo) NurseryCONTEXT: Adequacy of glucose infusion may be monitored via the glycosuria levels, as there is a relationship between glycemia and glycosuria regulated by the renal glucose threshold. In the neonatal period, however, this relationship is not so clear. OBJECTIVE: To evaluate the occurrence of glycosuria in preterm infants submitted to glucose infusion and to verify the relationship between glycosuria and blood glucose level. DESIGN: Accuracy study. SETTING: Neonatal intensive care unit of General Maternity Hospital. PATIENTS: 40 preterm newborns receiving glucose infusion. PROCEDURES: 511 concomitant determinations of glycemia and glycosuria were performed. These 511 pairs were divided into stable and unstable, according to the clinical status of the newborn at the time of data collection, and they were studied in relation to the gestational age, birth weight and glucose infusion rate. RESULTS: The results revealed a greater frequency of glycosuria in gestational age <FONT FACE="Symbol">£</font> 30 weeks, birth weight <1500 g and glucose infusion rate > 6 mg/kg/min. Eight (25.8%) episodes of positive glycosuria occurred in the absence of hyperglycemia, indicating only a moderate concordance between them. CONCLUSION: Glycosuria alone is an unreliable marker of blood glucose concentration and adequacy of glucose infusion rate. It is therefore necessary to monitor blood glucose levels in infants submitted to continuous glucose infusion.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000100004&lng=en&tlng=enBlood GlucoseGlycosuriaHyperglycemiaNewborn InfantParenteral Infusion |
| spellingShingle | Mário Cícero Falcão Cléa Rodrigues Leone José Lauro Araújo Ramos Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? São Paulo Medical Journal Blood Glucose Glycosuria Hyperglycemia Newborn Infant Parenteral Infusion |
| title | Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? |
| title_full | Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? |
| title_fullStr | Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? |
| title_full_unstemmed | Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? |
| title_short | Is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants? |
| title_sort | is glycosuria a reliable indicator of adequacy of glucose infusion rate in preterm infants |
| topic | Blood Glucose Glycosuria Hyperglycemia Newborn Infant Parenteral Infusion |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31801999000100004&lng=en&tlng=en |
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