Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience
Objectives: The aim of our study is to describe the various anesthetic techniques and intraoperative management used during transcatheter closure of hemodynamically significant PDAs in VLBW premature infants weighing less than 1.5 kg and their potential impact on postoperative outcomes using a retro...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S240584402304673X |
| _version_ | 1797771556050436096 |
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| author | Mikel Gorbea |
| author_facet | Mikel Gorbea |
| author_sort | Mikel Gorbea |
| collection | DOAJ |
| description | Objectives: The aim of our study is to describe the various anesthetic techniques and intraoperative management used during transcatheter closure of hemodynamically significant PDAs in VLBW premature infants weighing less than 1.5 kg and their potential impact on postoperative outcomes using a retrospective chart review. Design: A retrospective electronic medical chart review was performed in infants who underwent Transcatheter Patent Ductus Arteriosus (TC-PDA) closure at an academic institution between January 1, 2008 and October 4th 2019. Only premature patients with isolated PDA weighing less than 1500 g at the time of the procedure were included in the study. Setting: Single Institutional Hospital. Participants: Premature patients with isolated PDA weighing less than 1500 g at the time of the procedure. Interventions: None. Measurements and main results: Interprocedurally, there was no evidence of device embolization or clinically significant vascular obstruction on follow-up echocardiography, and inotropic or vasoactive infusions were not required. All patients survived and were discharged from the hospital after a mean of 86.4 ± 48.49 days (median 74, range 40–180) following initial admission to the NICU. At 7 post-operative days, freedom from ventilatory support reached 70% in all patients. Incidences of device embolization or clinically significant vascular obstruction were not noted on follow-up echocardiography. Conclusions: Though our preliminary findings show promising outcomes following TC-PDA closure relative to traditional surgical approaches, further investigations with higher patient volume are needed to validate these promising observations. |
| first_indexed | 2024-03-12T21:39:19Z |
| format | Article |
| id | doaj.art-3f9f5397e7234690ad8f55ff28f0cc28 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T21:39:19Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-3f9f5397e7234690ad8f55ff28f0cc282023-07-27T05:56:32ZengElsevierHeliyon2405-84402023-07-0197e17465Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experienceMikel Gorbea0Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, TX, USAObjectives: The aim of our study is to describe the various anesthetic techniques and intraoperative management used during transcatheter closure of hemodynamically significant PDAs in VLBW premature infants weighing less than 1.5 kg and their potential impact on postoperative outcomes using a retrospective chart review. Design: A retrospective electronic medical chart review was performed in infants who underwent Transcatheter Patent Ductus Arteriosus (TC-PDA) closure at an academic institution between January 1, 2008 and October 4th 2019. Only premature patients with isolated PDA weighing less than 1500 g at the time of the procedure were included in the study. Setting: Single Institutional Hospital. Participants: Premature patients with isolated PDA weighing less than 1500 g at the time of the procedure. Interventions: None. Measurements and main results: Interprocedurally, there was no evidence of device embolization or clinically significant vascular obstruction on follow-up echocardiography, and inotropic or vasoactive infusions were not required. All patients survived and were discharged from the hospital after a mean of 86.4 ± 48.49 days (median 74, range 40–180) following initial admission to the NICU. At 7 post-operative days, freedom from ventilatory support reached 70% in all patients. Incidences of device embolization or clinically significant vascular obstruction were not noted on follow-up echocardiography. Conclusions: Though our preliminary findings show promising outcomes following TC-PDA closure relative to traditional surgical approaches, further investigations with higher patient volume are needed to validate these promising observations.http://www.sciencedirect.com/science/article/pii/S240584402304673XPatent ductus arteriosus (PDA)Occlusion deviceNeonatalPediatricsPrematureLow-birth weight |
| spellingShingle | Mikel Gorbea Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience Heliyon Patent ductus arteriosus (PDA) Occlusion device Neonatal Pediatrics Premature Low-birth weight |
| title | Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience |
| title_full | Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience |
| title_fullStr | Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience |
| title_full_unstemmed | Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience |
| title_short | Perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter PDA (TC-PDA) closure: An institutional anesthetic experience |
| title_sort | perioperative anesthetic management of premature neonates weighing less than 1500 grams undergoing transcatheter pda tc pda closure an institutional anesthetic experience |
| topic | Patent ductus arteriosus (PDA) Occlusion device Neonatal Pediatrics Premature Low-birth weight |
| url | http://www.sciencedirect.com/science/article/pii/S240584402304673X |
| work_keys_str_mv | AT mikelgorbea perioperativeanestheticmanagementofprematureneonatesweighinglessthan1500gramsundergoingtranscatheterpdatcpdaclosureaninstitutionalanestheticexperience |