Characterization of the Synergistic Inhibition of <i>I</i><sub>K(erg)</sub> and <i>I</i><sub>K(DR)</sub> by Ribociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor
Ribociclib (RIB, LE011, Kisqali<sup>®</sup>), an orally administered inhibitor of cyclin-dependent kinase-4/6 (CDK-4/6) complex, is clinically effective for the treatment of several malignancies, including advanced breast cancer. However, information regarding the effects of RIB on membr...
Main Authors: | Pin-Yen Liu, Wei-Ting Chang, Sheng-Nan Wu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/21/8078 |
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