Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis
Abstract Background Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed when disease symptoms worsen and organ function deteriorates. In pulmonary sarcoidosis, prednisone and methotrexate (MTX) are the most common anti-inflammatory t...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-04-01
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Series: | Respiratory Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12931-024-02809-y |