Deletion of PGAM5 Downregulates FABP1 and Attenuates Long-Chain Fatty Acid Uptake in Hepatocellular Carcinoma

Deletion of PGAM5 Downregulates FABP1 and Attenuates Long-Chain Fatty Acid Uptake in Hepatocellular Carcinoma

Phosphoglycerate mutase 5 (PGAM5) is a Ser/His/Thr phosphatase responsible for regulating mitochondrial homeostasis. Overexpression of PGAM5 is correlated with a poor prognosis in hepatocellular carcinoma, colon cancer, and melanoma. In hepatocellular carcinoma, silencing of PGAM5 reduces growth, wh...

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Bibliographic Details
Main Authors:	Ganesan Muthusamy, Chin-Chi Liu, Andrea N. Johnston
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	Cancers
Subjects:	liver cancer long-chain fatty acids fatty acid transporters
Online Access:	https://www.mdpi.com/2072-6694/15/19/4796

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