Recent advances in the utilization of zeolite-based materials for controlled drug delivery
The advancement of zeolites and their application in the pharmaceutical field are fascinating topics to discuss and explore. This review will describe the zeolite manufacturing methods employed for drug delivery, including encapsulation, granulation, and spray drying. The crucial factor that must be...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715623001492 |
| _version_ | 1797798999982342144 |
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| author | Grandprix T.M. Kadja Neng T.U. Culsum Rindia M. Putri |
| author_facet | Grandprix T.M. Kadja Neng T.U. Culsum Rindia M. Putri |
| author_sort | Grandprix T.M. Kadja |
| collection | DOAJ |
| description | The advancement of zeolites and their application in the pharmaceutical field are fascinating topics to discuss and explore. This review will describe the zeolite manufacturing methods employed for drug delivery, including encapsulation, granulation, and spray drying. The crucial factor that must be considered in drug delivery system based on zeolites is the characteristics of the zeolite, including pore size, Si/Al ratio, and hydrophobicity, which can affect the loading capacity and the drug release process. The drug release from zeolite commonly involves an ion exchange mechanism. Various zeolites, including FAU, BEA, MFI, and CLI, have been employed as drug carriers for 5-fluorouracil (5-FU), ibuprofen, aspirin, diclofenac sodium, indomethacin, levofloxacin, and doxorubicin hydrochloride (DOX). Therefore, this review will comprehensively discuss the advancement of zeolites as drug carriers. |
| first_indexed | 2024-03-13T04:13:22Z |
| format | Article |
| id | doaj.art-3fa41ededf8a410f904a4dcd99f1e1f8 |
| institution | Directory Open Access Journal |
| issn | 2211-7156 |
| language | English |
| last_indexed | 2024-03-13T04:13:22Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj.art-3fa41ededf8a410f904a4dcd99f1e1f82023-06-21T06:52:32ZengElsevierResults in Chemistry2211-71562023-01-015100910Recent advances in the utilization of zeolite-based materials for controlled drug deliveryGrandprix T.M. Kadja0Neng T.U. Culsum1Rindia M. Putri2Division of Inorganic and Physical Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, Indonesia; Center for Catalysis and Reaction Engineering, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, Indonesia; Research Center for Nanosciences and Nanotechnology, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, Indonesia; Corresponding author at: Division of Inorganic and Physical Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, Indonesia.Division of Inorganic and Physical Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, IndonesiaBiochemistry Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jl. Ganesha no. 10, Bandung 40132, IndonesiaThe advancement of zeolites and their application in the pharmaceutical field are fascinating topics to discuss and explore. This review will describe the zeolite manufacturing methods employed for drug delivery, including encapsulation, granulation, and spray drying. The crucial factor that must be considered in drug delivery system based on zeolites is the characteristics of the zeolite, including pore size, Si/Al ratio, and hydrophobicity, which can affect the loading capacity and the drug release process. The drug release from zeolite commonly involves an ion exchange mechanism. Various zeolites, including FAU, BEA, MFI, and CLI, have been employed as drug carriers for 5-fluorouracil (5-FU), ibuprofen, aspirin, diclofenac sodium, indomethacin, levofloxacin, and doxorubicin hydrochloride (DOX). Therefore, this review will comprehensively discuss the advancement of zeolites as drug carriers.http://www.sciencedirect.com/science/article/pii/S2211715623001492ZeoliteDrug deliveryEncapsulationAnti-cancer |
| spellingShingle | Grandprix T.M. Kadja Neng T.U. Culsum Rindia M. Putri Recent advances in the utilization of zeolite-based materials for controlled drug delivery Results in Chemistry Zeolite Drug delivery Encapsulation Anti-cancer |
| title | Recent advances in the utilization of zeolite-based materials for controlled drug delivery |
| title_full | Recent advances in the utilization of zeolite-based materials for controlled drug delivery |
| title_fullStr | Recent advances in the utilization of zeolite-based materials for controlled drug delivery |
| title_full_unstemmed | Recent advances in the utilization of zeolite-based materials for controlled drug delivery |
| title_short | Recent advances in the utilization of zeolite-based materials for controlled drug delivery |
| title_sort | recent advances in the utilization of zeolite based materials for controlled drug delivery |
| topic | Zeolite Drug delivery Encapsulation Anti-cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2211715623001492 |
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