Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level
Hypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the pro...
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| Format: | Article |
| Language: | English |
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Permanyer
2022-04-01
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| Series: | Revista Mexicana de Neurociencia |
| Subjects: | |
| Online Access: | https://www.revmexneurociencia.com/frame_esp.php?id=174 |
| _version_ | 1819277425727504384 |
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| author | Clara L. Ramirez-Rincón |
| author_facet | Clara L. Ramirez-Rincón |
| author_sort | Clara L. Ramirez-Rincón |
| collection | DOAJ |
| description | Hypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the process of neurogenesis, which involves various stages, such as proliferation of neuronal stem cells, migration, differentiation, survival of new neurons, and integration of the same. Among the many intrinsic and extrinsic molecular signals that regulate the production of new neurons from progenitor cells in the adult in the central nervous system (CNS), hypoxic damage plays an important role in the maintenance and function of stem cells in development and disease.
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| first_indexed | 2024-12-23T23:55:55Z |
| format | Article |
| id | doaj.art-3fa71fd0f3a5494d9e5779395a02e14d |
| institution | Directory Open Access Journal |
| issn | 2604-6180 |
| language | English |
| last_indexed | 2024-12-23T23:55:55Z |
| publishDate | 2022-04-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista Mexicana de Neurociencia |
| spelling | doaj.art-3fa71fd0f3a5494d9e5779395a02e14d2022-12-21T17:25:15ZengPermanyerRevista Mexicana de Neurociencia2604-61802022-04-0123210.24875/RMN.21000020Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal levelClara L. Ramirez-Rincón0School of Health Sciences, University of the Valley of Mexico, Zapopan, Jalisco, MexicoHypoxia-induced factor 1 (HIF-1) plays a fundamental role in the response to low oxygen tension, since it regulates the expression of a wide variety of genes, whose products participate in processes such as angiogenesis, energy metabolism, erythropoiesis, and cell proliferation as well as in the process of neurogenesis, which involves various stages, such as proliferation of neuronal stem cells, migration, differentiation, survival of new neurons, and integration of the same. Among the many intrinsic and extrinsic molecular signals that regulate the production of new neurons from progenitor cells in the adult in the central nervous system (CNS), hypoxic damage plays an important role in the maintenance and function of stem cells in development and disease. https://www.revmexneurociencia.com/frame_esp.php?id=174HIF. Neurogénesis. Hippocampus. Hypoxic. Wnt-catenin. |
| spellingShingle | Clara L. Ramirez-Rincón Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level Revista Mexicana de Neurociencia HIF. Neurogénesis. Hippocampus. Hypoxic. Wnt-catenin. |
| title | Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level |
| title_full | Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level |
| title_fullStr | Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level |
| title_full_unstemmed | Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level |
| title_short | Role of the hypoxia-inducible factor (HIF) in the process of neurogenesis at the hippocampal level |
| title_sort | role of the hypoxia inducible factor hif in the process of neurogenesis at the hippocampal level |
| topic | HIF. Neurogénesis. Hippocampus. Hypoxic. Wnt-catenin. |
| url | https://www.revmexneurociencia.com/frame_esp.php?id=174 |
| work_keys_str_mv | AT claralramirezrincon roleofthehypoxiainduciblefactorhifintheprocessofneurogenesisatthehippocampallevel |