Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens
Complex interactions between bacteriophages and their bacterial hosts play significant roles in shaping the structure of environmental microbial communities, not only by genetic transduction but also by modification of bacterial gene expression patterns. Survival of phages solely depends on their ab...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2014-08-01
|
| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00442/full |
| _version_ | 1828416649057796096 |
|---|---|
| author | Soraya eChaturongakul Soraya eChaturongakul Puey eOunjai |
| author_facet | Soraya eChaturongakul Soraya eChaturongakul Puey eOunjai |
| author_sort | Soraya eChaturongakul |
| collection | DOAJ |
| description | Complex interactions between bacteriophages and their bacterial hosts play significant roles in shaping the structure of environmental microbial communities, not only by genetic transduction but also by modification of bacterial gene expression patterns. Survival of phages solely depends on their ability to infect their bacterial hosts, most importantly during phage entry. Successful dynamic adaptation of bacteriophages when facing selective pressures, such as host adaptation and resistance, dictates their abundance and diversification. Co-evolution of the phage tail fibers and bacterial receptors determine bacterial host ranges, mechanisms of phage entry and other infection parameters. This review summarizes the current knowledge about the physical interactions between tailed bacteriophages and bacterial pathogens (e.g., Salmonella enterica and Pseudomonas aeruginosa) and the influences of the phage on host gene expression. Understanding these interactions can offer insights into phage-host dynamics and suggest novel strategies for the design of bacterial pathogen biological controls. |
| first_indexed | 2024-12-10T14:06:19Z |
| format | Article |
| id | doaj.art-3fa76d8f3343445c961556102c22b049 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-10T14:06:19Z |
| publishDate | 2014-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-3fa76d8f3343445c961556102c22b0492022-12-22T01:45:39ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2014-08-01510.3389/fmicb.2014.0044298825Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogensSoraya eChaturongakul0Soraya eChaturongakul1Puey eOunjai2Mahidol UniversityMahidol UniversityMahidol UniversityComplex interactions between bacteriophages and their bacterial hosts play significant roles in shaping the structure of environmental microbial communities, not only by genetic transduction but also by modification of bacterial gene expression patterns. Survival of phages solely depends on their ability to infect their bacterial hosts, most importantly during phage entry. Successful dynamic adaptation of bacteriophages when facing selective pressures, such as host adaptation and resistance, dictates their abundance and diversification. Co-evolution of the phage tail fibers and bacterial receptors determine bacterial host ranges, mechanisms of phage entry and other infection parameters. This review summarizes the current knowledge about the physical interactions between tailed bacteriophages and bacterial pathogens (e.g., Salmonella enterica and Pseudomonas aeruginosa) and the influences of the phage on host gene expression. Understanding these interactions can offer insights into phage-host dynamics and suggest novel strategies for the design of bacterial pathogen biological controls.http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00442/fullmicrobial communityBacteriophagehost-phage interactionhost-phage dynamicsphage resistance mechanism |
| spellingShingle | Soraya eChaturongakul Soraya eChaturongakul Puey eOunjai Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens Frontiers in Microbiology microbial community Bacteriophage host-phage interaction host-phage dynamics phage resistance mechanism |
| title | Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens |
| title_full | Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens |
| title_fullStr | Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens |
| title_full_unstemmed | Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens |
| title_short | Phage-host interplay: examples from tailed phages and Gram-negative bacterial pathogens |
| title_sort | phage host interplay examples from tailed phages and gram negative bacterial pathogens |
| topic | microbial community Bacteriophage host-phage interaction host-phage dynamics phage resistance mechanism |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00442/full |
| work_keys_str_mv | AT sorayaechaturongakul phagehostinterplayexamplesfromtailedphagesandgramnegativebacterialpathogens AT sorayaechaturongakul phagehostinterplayexamplesfromtailedphagesandgramnegativebacterialpathogens AT pueyeounjai phagehostinterplayexamplesfromtailedphagesandgramnegativebacterialpathogens |