Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis

Giardia duodenalis is the causative agent of the neglected diarrhoeal disease giardiasis. While often self-limiting, giardiasis is ubiquitous and impacts hundreds of millions of people annually. It is also a common gastro-intestinal disease of domestic pets, wildlife, and livestock animals. However,...

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Bibliographic Details
Main Authors: Christopher JS. Hart, Andrew G. Riches, Snigdha Tiash, Rebecca Abraham, Keely Fayd’Herbe, Ellis Joch, Bilal Zulfiqar, Melissa L. Sykes, Vicky M. Avery, Jan Šlapeta, Sam Abraham, John H. Ryan, Tina S. Skinner-Adams
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Subjects:
Giardia duodenalis
Drug discovery
Thieno[3,2-b]pyrrole 5-carboxamides
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320723000295

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