Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade

Chibby suppresses aerobic glycolysis and proliferation of nasopharyngeal carcinoma via the Wnt/β-catenin-Lin28/let7-PDK1 cascade

Abstract Background Great progress has been achieved in the study of the aerobic glycolysis or the so-called Warburg effect in a variety of cancers; however, the regulation of the Warburg effect in Nasopharyngeal carcinoma (NPC) has not been completely defined. Methods Gene expression pattern of NPC...

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Bibliographic Details
Main Authors: Cheng-fu Cai, Guo-dong Ye, Dong-yan Shen, Wei Zhang, Mao-li Chen, Xin-xin Chen, Da-xiong Han, Yan-jun Mi, Qi-cong Luo, Wang-yu Cai, Shu-yu Yang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Chibby
Warburg effect
Wnt/β-Catenin signaling
Nasopharyngeal carcinoma
Online Access:http://link.springer.com/article/10.1186/s13046-018-0769-4

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