Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery

Intra-operative target pose estimation is fundamental in minimally invasive surgery (MIS) to guiding surgical robots. This task can be fulfilled by the 2-D/3-D rigid registration, which aligns the anatomical structures between intra-operative 2-D fluoroscopy and the pre-operative 3-D computed tomogr...

Full description

Bibliographic Details
Main Authors: Zhou An, Honghai Ma, Lilu Liu, Yue Wang, Haojian Lu, Chunlin Zhou, Rong Xiong, Jian Hu
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/12/7/844
_version_ 1797526577432494080
author Zhou An
Honghai Ma
Lilu Liu
Yue Wang
Haojian Lu
Chunlin Zhou
Rong Xiong
Jian Hu
author_facet Zhou An
Honghai Ma
Lilu Liu
Yue Wang
Haojian Lu
Chunlin Zhou
Rong Xiong
Jian Hu
author_sort Zhou An
collection DOAJ
description Intra-operative target pose estimation is fundamental in minimally invasive surgery (MIS) to guiding surgical robots. This task can be fulfilled by the 2-D/3-D rigid registration, which aligns the anatomical structures between intra-operative 2-D fluoroscopy and the pre-operative 3-D computed tomography (CT) with annotated target information. Although this technique has been researched for decades, it is still challenging to achieve accuracy, robustness and efficiency simultaneously. In this paper, a novel orthogonal-view 2-D/3-D rigid registration framework is proposed which combines the dense reconstruction based on deep learning and the GPU-accelerated 3-D/3-D rigid registration. First, we employ the X2CT-GAN to reconstruct a target CT from two orthogonal fluoroscopy images. After that, the generated target CT and pre-operative CT are input into the 3-D/3-D rigid registration part, which potentially needs a few iterations to converge the global optima. For further efficiency improvement, we make the 3-D/3-D registration algorithm parallel and apply a GPU to accelerate this part. For evaluation, a novel tool is employed to preprocess the public head CT dataset CQ500 and a CT-DRR dataset is presented as the benchmark. The proposed method achieves 1.65 ± 1.41 mm in mean target registration error(mTRE), 20% in the gross failure rate(GFR) and 1.8 s in running time. Our method outperforms the state-of-the-art methods in most test cases. It is promising to apply the proposed method in localization and nano manipulation of micro surgical robot for highly precise MIS.
first_indexed 2024-03-10T09:31:19Z
format Article
id doaj.art-3fadaa4f7207424f9b272aecca33b27b
institution Directory Open Access Journal
issn 2072-666X
language English
last_indexed 2024-03-10T09:31:19Z
publishDate 2021-07-01
publisher MDPI AG
record_format Article
series Micromachines
spelling doaj.art-3fadaa4f7207424f9b272aecca33b27b2023-11-22T04:25:23ZengMDPI AGMicromachines2072-666X2021-07-0112784410.3390/mi12070844Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive SurgeryZhou An0Honghai Ma1Lilu Liu2Yue Wang3Haojian Lu4Chunlin Zhou5Rong Xiong6Jian Hu7Department of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaDepartment of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaState Key Laboratory of Industrial Control and Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Industrial Control and Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Industrial Control and Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Industrial Control and Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Industrial Control and Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaDepartment of Thoracic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, ChinaIntra-operative target pose estimation is fundamental in minimally invasive surgery (MIS) to guiding surgical robots. This task can be fulfilled by the 2-D/3-D rigid registration, which aligns the anatomical structures between intra-operative 2-D fluoroscopy and the pre-operative 3-D computed tomography (CT) with annotated target information. Although this technique has been researched for decades, it is still challenging to achieve accuracy, robustness and efficiency simultaneously. In this paper, a novel orthogonal-view 2-D/3-D rigid registration framework is proposed which combines the dense reconstruction based on deep learning and the GPU-accelerated 3-D/3-D rigid registration. First, we employ the X2CT-GAN to reconstruct a target CT from two orthogonal fluoroscopy images. After that, the generated target CT and pre-operative CT are input into the 3-D/3-D rigid registration part, which potentially needs a few iterations to converge the global optima. For further efficiency improvement, we make the 3-D/3-D registration algorithm parallel and apply a GPU to accelerate this part. For evaluation, a novel tool is employed to preprocess the public head CT dataset CQ500 and a CT-DRR dataset is presented as the benchmark. The proposed method achieves 1.65 ± 1.41 mm in mean target registration error(mTRE), 20% in the gross failure rate(GFR) and 1.8 s in running time. Our method outperforms the state-of-the-art methods in most test cases. It is promising to apply the proposed method in localization and nano manipulation of micro surgical robot for highly precise MIS.https://www.mdpi.com/2072-666X/12/7/8442-D/3-D registrationrigidmulti-viewreconstructiondeep learning
spellingShingle Zhou An
Honghai Ma
Lilu Liu
Yue Wang
Haojian Lu
Chunlin Zhou
Rong Xiong
Jian Hu
Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
Micromachines
2-D/3-D registration
rigid
multi-view
reconstruction
deep learning
title Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
title_full Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
title_fullStr Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
title_full_unstemmed Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
title_short Robust Orthogonal-View 2-D/3-D Rigid Registration for Minimally Invasive Surgery
title_sort robust orthogonal view 2 d 3 d rigid registration for minimally invasive surgery
topic 2-D/3-D registration
rigid
multi-view
reconstruction
deep learning
url https://www.mdpi.com/2072-666X/12/7/844
work_keys_str_mv AT zhouan robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT honghaima robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT liluliu robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT yuewang robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT haojianlu robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT chunlinzhou robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT rongxiong robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery
AT jianhu robustorthogonalview2d3drigidregistrationforminimallyinvasivesurgery