Echovirus 11 infection induces pyroptotic cell death by facilitating NLRP3 inflammasome activation.

Echovirus 11 (ECHO 11) is a positive-strand RNA virus belonging to the genus Enterovirus of the family Picornaviridae. ECHO 11 infections can cause severe inflammatory illnesses in neonates, including severe acute hepatitis with coagulopathy. The activation of NLRP3 inflammasome is important for hos...

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Bibliographic Details
Main Authors: Chong Wang, Ruyi Yang, Fengxia Yang, Yang Han, Yujie Ren, Xiaobei Xiong, Xingyun Wang, Yidan Bi, Lijun Li, Yang Qiu, Yi Xu, Xi Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010787

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