Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China
Abstract Background Fear of a global public health issue and fresh infection wave in the persistent COVID-19 pandemic has been enflamed by the appearance of the novel variant Omicron BF.7 lineage. Recently, it has been seeing the novel Omicron subtype BF.7 lineage has sprawled exponentially in Hohho...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-02-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-024-09084-8 |
| _version_ | 1797275675566014464 |
|---|---|
| author | Yanhai Wang Guohui Yu Jingru Shi Xiaqing Zhang Jianxin Huo Meng Li Jiaxi Chen Liyuan Yu Yan Li Zhiliang Han Jianwen Zhang Xuna Ren Yujie Wang Wu Yuntana |
| author_facet | Yanhai Wang Guohui Yu Jingru Shi Xiaqing Zhang Jianxin Huo Meng Li Jiaxi Chen Liyuan Yu Yan Li Zhiliang Han Jianwen Zhang Xuna Ren Yujie Wang Wu Yuntana |
| author_sort | Yanhai Wang |
| collection | DOAJ |
| description | Abstract Background Fear of a global public health issue and fresh infection wave in the persistent COVID-19 pandemic has been enflamed by the appearance of the novel variant Omicron BF.7 lineage. Recently, it has been seeing the novel Omicron subtype BF.7 lineage has sprawled exponentially in Hohhot. More than anything, risk stratification is significant to ascertain patients infected with COVID-19 who the most need in-hospital or in-home management. The study intends to understand the clinical severity and epidemiological characteristics of COVID-19 Omicron subvariant BF.7. lineage via gathering and analyzing the cases with Omicron subvariant in Hohhot, Inner Mongolia. Methods Based upon this, we linked variant Omicron BF.7 individual-level information including sex, age, symptom, underlying conditions and vaccination record. Further, we divided the cases into various groups and assessed the severity of patients according to the symptoms of patients with COVID-19. Clinical indicators and data might help to predict disadvantage outcomes and progression among Omicron BF.7 patients. Results In this study, in patients with severe symptoms, some indicators from real world data such as white blood cells, AST, ALT and CRE in patients with Omicron BF.7 in severe symptoms were significantly higher than mild and asymptomatic patients, while some indicators were significantly lower. Conclusions Above results suggested that the indicators were associated with ponderance of clinical symptoms. Our survey emphasized the value of timely investigations of clinical data obtained by systemic study to acquire detailed information. |
| first_indexed | 2024-03-07T15:17:54Z |
| format | Article |
| id | doaj.art-3fb5e988ca2d4ce0b6c807e8a29f44a8 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-03-07T15:17:54Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-3fb5e988ca2d4ce0b6c807e8a29f44a82024-03-05T17:49:11ZengBMCBMC Infectious Diseases1471-23342024-02-0124111210.1186/s12879-024-09084-8Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, ChinaYanhai Wang0Guohui Yu1Jingru Shi2Xiaqing Zhang3Jianxin Huo4Meng Li5Jiaxi Chen6Liyuan Yu7Yan Li8Zhiliang Han9Jianwen Zhang10Xuna Ren11Yujie Wang12Wu Yuntana13Clinical Laboratory Department, Hohhot First HospitalHohhot Dian Medical Laboratory, Key Laboratory of Digital Technology in Medical Diagnostics of Zhejiang Province, Dian Diagnostics Group Co., Ltd. NoClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalClinical Laboratory Department, Hohhot First HospitalAbstract Background Fear of a global public health issue and fresh infection wave in the persistent COVID-19 pandemic has been enflamed by the appearance of the novel variant Omicron BF.7 lineage. Recently, it has been seeing the novel Omicron subtype BF.7 lineage has sprawled exponentially in Hohhot. More than anything, risk stratification is significant to ascertain patients infected with COVID-19 who the most need in-hospital or in-home management. The study intends to understand the clinical severity and epidemiological characteristics of COVID-19 Omicron subvariant BF.7. lineage via gathering and analyzing the cases with Omicron subvariant in Hohhot, Inner Mongolia. Methods Based upon this, we linked variant Omicron BF.7 individual-level information including sex, age, symptom, underlying conditions and vaccination record. Further, we divided the cases into various groups and assessed the severity of patients according to the symptoms of patients with COVID-19. Clinical indicators and data might help to predict disadvantage outcomes and progression among Omicron BF.7 patients. Results In this study, in patients with severe symptoms, some indicators from real world data such as white blood cells, AST, ALT and CRE in patients with Omicron BF.7 in severe symptoms were significantly higher than mild and asymptomatic patients, while some indicators were significantly lower. Conclusions Above results suggested that the indicators were associated with ponderance of clinical symptoms. Our survey emphasized the value of timely investigations of clinical data obtained by systemic study to acquire detailed information.https://doi.org/10.1186/s12879-024-09084-8Global public healthOutbreakClinical indicatorsOmicron BF.7Risk stratification |
| spellingShingle | Yanhai Wang Guohui Yu Jingru Shi Xiaqing Zhang Jianxin Huo Meng Li Jiaxi Chen Liyuan Yu Yan Li Zhiliang Han Jianwen Zhang Xuna Ren Yujie Wang Wu Yuntana Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China BMC Infectious Diseases Global public health Outbreak Clinical indicators Omicron BF.7 Risk stratification |
| title | Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China |
| title_full | Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China |
| title_fullStr | Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China |
| title_full_unstemmed | Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China |
| title_short | Retrospective study about clinical severity and epidemiological analysis of the COVID-19 Omicron subvariant lineage-infected patients in Hohhot, China |
| title_sort | retrospective study about clinical severity and epidemiological analysis of the covid 19 omicron subvariant lineage infected patients in hohhot china |
| topic | Global public health Outbreak Clinical indicators Omicron BF.7 Risk stratification |
| url | https://doi.org/10.1186/s12879-024-09084-8 |
| work_keys_str_mv | AT yanhaiwang retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT guohuiyu retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT jingrushi retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT xiaqingzhang retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT jianxinhuo retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT mengli retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT jiaxichen retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT liyuanyu retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT yanli retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT zhilianghan retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT jianwenzhang retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT xunaren retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT yujiewang retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina AT wuyuntana retrospectivestudyaboutclinicalseverityandepidemiologicalanalysisofthecovid19omicronsubvariantlineageinfectedpatientsinhohhotchina |