Effect of induced epilepsy on some biochemical parameters in female rats
The activity of cholinesterase and some biochemical parameters of blood such as glucose, cholesterol and phospholipids were estimated in 52 epilepsy induced females of Wister albino rats. Animals of this experiment were divided into two groups, group (I) regarded as control and group (II) administra...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Veterinary Medicine
2012-01-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://www.vetmedmosul.org/ijvs/media/12-2-7e.pdf |
| _version_ | 1818542320992124928 |
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| author | J.S. H. Ali L.I. Matty S.S. Yahya |
| author_facet | J.S. H. Ali L.I. Matty S.S. Yahya |
| author_sort | J.S. H. Ali |
| collection | DOAJ |
| description | The activity of cholinesterase and some biochemical parameters of blood such as glucose, cholesterol and phospholipids were estimated in 52 epilepsy induced females of Wister albino rats. Animals of this experiment were divided into two groups, group (I) regarded as control and group (II) administrated subcutaneously by pentylenetetrazole 100mg/kg and divided in to three sub-groups according to the time of samples collection 3 hrs, 24 hrs and 1 week. The results revealed that epilepsy induction caused a significant inhibition of serum cholinesterase activity 3 hrs after induction while in the brain, the activity of cholinesterase was significantly increased after 24 hrs Serum glucose level was significantly elevated after 3 hrs and 24 hrs of induction, total cholesterol and phospholipids were not changed. From the results obtained in this study, it can be concluded that epilepsy caused significant changes in cholinesterase activity in brain and serum in addition to the glucose level in the serum. |
| first_indexed | 2024-12-11T22:20:32Z |
| format | Article |
| id | doaj.art-3fb6c09da6e24c429161ed48b3857a34 |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-12-11T22:20:32Z |
| publishDate | 2012-01-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-3fb6c09da6e24c429161ed48b3857a342022-12-22T00:48:28ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552012-01-012628992Effect of induced epilepsy on some biochemical parameters in female ratsJ.S. H. AliL.I. MattyS.S. YahyaThe activity of cholinesterase and some biochemical parameters of blood such as glucose, cholesterol and phospholipids were estimated in 52 epilepsy induced females of Wister albino rats. Animals of this experiment were divided into two groups, group (I) regarded as control and group (II) administrated subcutaneously by pentylenetetrazole 100mg/kg and divided in to three sub-groups according to the time of samples collection 3 hrs, 24 hrs and 1 week. The results revealed that epilepsy induction caused a significant inhibition of serum cholinesterase activity 3 hrs after induction while in the brain, the activity of cholinesterase was significantly increased after 24 hrs Serum glucose level was significantly elevated after 3 hrs and 24 hrs of induction, total cholesterol and phospholipids were not changed. From the results obtained in this study, it can be concluded that epilepsy caused significant changes in cholinesterase activity in brain and serum in addition to the glucose level in the serum.http://www.vetmedmosul.org/ijvs/media/12-2-7e.pdfEpilepsyPentyleneterazoleCholinesterase |
| spellingShingle | J.S. H. Ali L.I. Matty S.S. Yahya Effect of induced epilepsy on some biochemical parameters in female rats Iraqi Journal of Veterinary Sciences Epilepsy Pentyleneterazole Cholinesterase |
| title | Effect of induced epilepsy on some biochemical parameters in female rats |
| title_full | Effect of induced epilepsy on some biochemical parameters in female rats |
| title_fullStr | Effect of induced epilepsy on some biochemical parameters in female rats |
| title_full_unstemmed | Effect of induced epilepsy on some biochemical parameters in female rats |
| title_short | Effect of induced epilepsy on some biochemical parameters in female rats |
| title_sort | effect of induced epilepsy on some biochemical parameters in female rats |
| topic | Epilepsy Pentyleneterazole Cholinesterase |
| url | http://www.vetmedmosul.org/ijvs/media/12-2-7e.pdf |
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